New Possibilities in the Treatment of Migraine
Novější možnosti v léčbě migrény
Farmakologická léčba migrény zahrnuje léčbu akutního záchvatu (abortivní) a léčbu profylak-tickou (preventivní). Smyslem abortivní léčby je úleva od bolesti a přidružených příznaků přivlastní atace migrény. K léčbě akutního záchvatu se používají jednoduchá analgetika, neste-roidní antiflogistika, ergotové preparáty a triptany. Cílem profylaktické léčby je snížit frekvenci,trvání a intenzitu záchvatů. Nejužívanější profylaktika jsou betablokátory, blokátory kalcio-vých kanálů, antikonvulziva, antagonisté serotoninových (5-HT2) receptorů, antidepresiva a lzeužít i nesteroidní antiflogistika.
Klíčová slova:
migréna - léčba - abortivní a profylaktická léčba.
Authors:
R. Kotas
Authors‘ workplace:
Neurologická klinika LF UK a FN, Plzeň, přednosta prof. MUDr. Z. Ambler, DrSc.
Published in:
Prakt. Lék. 1999; (10): 578-580
Overview
The pharmacologic management of migraine includes abortive therapy (i.g. the treatment ofan acute attack) and prophylactic (preventive) therapy. The purpose of abortive therapy is therelief from headache and associated symptoms. Agents used in abortive therapy are simpleanalgesics, non-steroidal anti-inflammatory drugs, ergots and triptans. Prophylactic therapyis administered to reduce the frequency, duration and intensity of attacks. The most commonlyused prophylactic agents are beta-blockers, calcium channel blockers, anticonvulsants, seroto-nin (5-HT2) receptor antagonists and antidepressants. Non-steroidal anti-inflammatory drugscan be also used.
Key words:
migraine - therapy - abortive and prophylactic therapy.
Labels
General practitioner for children and adolescents General practitioner for adultsArticle was published in
General Practitioner
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