On the Fourth Itraconazole Pulse
Jak je to se čtvrtým pulzem itrakonazolu
Ačkoli v klinických studiích se ukázalo, že 3 pulzy itrakonazolu jsou dostačující pro vyléčenínekomplikované onychomykózy nohou, v běžné praxi tato dávka leckdy nepostačuje. Pacientis onychomykózou jsou často senioři s poruchami prokrvení dolních končetin a se zpomalením růstunehtu. Novější klinické studie dokazují v těchto případech prospěšnost přidání dalších pulzů itrakonazolu,a to buď formou prodloužení kúry ze 3 na 4 měsíce, nebo přidáním tzv. adičního pulzu za6 měsíců od začátku terapie.
Klíčová slova:
onychomykózy - itrakonazol - adiční pulz
Authors:
M. Skořepová
Authors‘ workplace:
Dermatovenerologická klinika 1. LF UK a VFN Praha přednosta doc. MUDr. J. Štork, CSc.
Published in:
Čes-slov Derm, , 2003, No. 3, p. 124-125
Category:
Overview
Although clinical studies revealed that three itraconazole pulses are sufficient to cure non-complicatedonychomycoses of the toe nails, in common practice this dose sometimes does not suffice.Patients with onychomycoses are frequently senior citizens with an impaired blood supply of thelower extremities and slow growth of the nails. Recent clinical studies indicate in these instancesthat it is useful to add further itraconazole pulses either by protraction of the treatment from 3 to 4months or to add a so-called additional pulse 6 months after the onset of therapy.
Key words:
onychomycoses - itraconazole - additional pulse
Labels
Dermatology & STDs Paediatric dermatology & STDsArticle was published in
Czech-Slovak Dermatology
2003 Issue 3
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