Acquired Hemophilia

Acquired hemophilia (AHA) typically manifests with spontaneous bleeding in patients with no prior personal history of significant bleeding.^1–4 The cause of the bleeding is a significant decrease in FVIII activity induced by autoantibodies against coagulation factor VIII.⁵ In polymorbid patients, established antithrombotic therapy at the time of AHA diagnosis may also contribute to the bleeding.⁴