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Mental Health During the Pandemic −⁠ and How to Alleviate Its Impacts

10. 1. 2022 Source: Depression and Anxiety

At the symposium during the XV Spring Interactive Conference of the General Medical Society of ČLS JEP, which was eventually held in September 2021 in Prague, Prof. MUDr. Cyril Höschl, DrSc., FRCPsych, presented his lecture on the impacts of the COVID-19 pandemic on mental health. At the end of his speech, he also addressed the practical issue of selecting a suitable antidepressant.

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Stabilization of Liver Metastases of CRC with Trifluridine/Tipiracil in 3rd Line Therapy –⁠ Case Study

We present a case study of a man born in 1944 who underwent resection of the rectosigmoid for multiple adenocarcinomas in February 2016. Subsequently discovered liver metastases were managed with…

10. 1. 2022 Source: Treatment of Gastrointestinal Carcinomas

Levodropropizine –⁠ a non-codeine antitussive with minimal side effects, contraindications, and drug interactions

For symptomatic treatment of dry, irritating, and exhausting cough, both codeine and non-codeine antitussives can be used. One of the non-codeine antitussives is levodropropizine. Its antitussive…

10. 1. 2022 Source: Cough Therapy

From Hell to the Light at the End of the Tunnel –⁠ A Task for Eletriptan

In recent months, under the spotlight of new biological treatments, the focus has been predominantly on the prophylactic treatment of migraines. However, we should not forget about acute therapy. In…

4. 1. 2022 Source: Treatment of Severe Migraine

Brentuximab Vedotin as Another Therapeutic Option in Cutaneous T-Cell Lymphoma

Current systemic treatment for patients with cutaneous T-cell lymphoma (CTCL) unfortunately has limited efficacy, achieving low response rates and short-lasting remissions. Moreover, there is no…

4. 1. 2022 Source: Hematologic Malignancies

Current Recommendations of the Expert Panel on the Management of von Willebrand Disease

Von Willebrand disease (vWD) is a common congenital bleeding disorder. The care of patients with vWD involves significant variability due to bleeding manifestations and treatment options. The new…

4. 1. 2022 Source: Von Willebrand Disease

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How and with What the National Registry of Primary Immunodeficiencies Benefits Specialists and Patients

Primary immunodeficiencies constitute a very heterogeneous group of congenital diseases. They affect both specific and nonspecific immunity and are classified accordingly. The care for patients with…

3. 1. 2022 Source: Hereditary Angioedema

Update of the Blue Book: What's New in the Treatment of Metastatic NSCLC with an ALK Gene Mutation?

As of March 1, 2022, the 28th update of the Blue Book by the Czech Society for Oncology of ČLS JEP was released. Let's take a look at what changes it has brought compared to the previous version in…

27. 12. 2021 Source: Genetic Profile and Treatment of NSCLC

Brain Metastases Are Not an Absolute Contraindication for Antiplatelet Therapy

On one hand, there's a higher risk of thromboembolic events, and on the other, a higher risk of intracranial bleeding. Prophylactic and therapeutic interventions for blood clotting are necessary for…

27. 12. 2021 Source: Genetic Profile and Treatment of NSCLC

Complete remission of ALK-positive lung cancer in a patient after multiple lines of targeted therapy –⁠ a case study

Targeted treatment for driving oncogenic mutations has significantly improved outcomes for patients with ALK-positive non-small cell lung cancer (NSCLC) as well. A case study was recently published…

27. 12. 2021 Source: Genetic Profile and Treatment of NSCLC

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