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Genetic Testing in Non-Small Cell Lung Cancer - Clinical Practice Experience
30. 9. 2020 Source: Genetic Profile and Treatment of NSCLCTargeted therapy has brought significant improvements to certain groups of patients with non-small cell lung cancer (NSCLC). Selecting patients who will benefit from targeted therapy can be performed using molecular profiling with next-generation sequencing (NGS) techniques. However, we still lack sufficient data on the feasibility and results of such profiling in real-world clinical practice, which was the focus of an analysis recently published in The Oncologist.
Stable Position of Micronized Diosmin in the Treatment of Chronic Venous Insufficiency and Hemorrhoids
Diosmin is a flavonoid used in Europe as a venotonic and vasoprotective agent for over 40 years. Significant progress has been made in medicine during this time, yet the role of diosmin in the…30. 9. 2020 Source: Venous Insufficiency
Adequate Compensation of a Hypertensive Patient According to Current ESC Guidelines – Case Study
A 65-year-old man, hypertensive, visits the general practitioner for a check-up. He reports recent shortness of breath during mild exertion (walking up stairs). Two months ago, he had acute sinusitis,...29. 9. 2020 Source: Sartans in the Treatment of Hypertension
Finger on the Pulse of the Times with Automated Peritoneal Dialysis and Remote Patient Monitoring
The method of peritoneal dialysis brings many advantages to patients with chronic kidney disease and significantly eases their lives. Peritoneal dialysis saves time for both the patients themselves…29. 9. 2020 Source: Chronic Kidney Disease
Shared Decision Making Plays an Important Role in Dialysis
Peritoneal dialysis is very effective and comfortable for patients, yet it is used relatively little in the Czech Republic. Are we giving enough room to patients' preferences?29. 9. 2020 Source: Chronic Kidney Disease
Polatuzumab Vedotin in the Treatment of NHL - News from the 25th EHA Congress
Polatuzumab vedotin (Polivy) is approved in the EU for the treatment of patients with relapsed/refractory diffuse large B-cell lymphoma (R/R DLBCL), for whom hematopoietic stem cell transplantation…29. 9. 2020 Source: Non-Hodgkin Lymphomas and CLL
How to Secure Diabetics with Atrial Fibrillation During PCI?
Optimal management of patients with atrial fibrillation undergoing percutaneous coronary intervention (PCI) continues to be the subject of studies. A sub-analysis of the RE-DUAL study focused on this…29. 9. 2020 Source: Anticoagulant Treatment
Safety of Dabigatran in the Secondary Prevention of Venous Thromboembolism in Children
The direct thrombin inhibitor dabigatran is used by adult patients, among others, in the secondary prevention of venous thromboembolism (VTE). Its safety in the pediatric population was the focus of…29. 9. 2020 Source: Anticoagulant Treatment
Is It Better to Switch or Cycle in the Treatment of Rheumatoid Arthritis?
The ideal strategy for treating rheumatoid arthritis is still the subject of research. We therefore present the results of a recent study comparing the impact of various therapeutic options when…24. 9. 2020 Source: Arthritis
Remarkable Findings from the Subanalysis of the Efficacy and Safety of Teriflunomide in the Chinese Population with MS in Relation to Global Results
Teriflunomide, from the group of disease-modifying drugs (DMDs), intended for the treatment of patients with multiple sclerosis (MS), inhibits the proliferation of lymphocytes. As a result, fewer…24. 9. 2020 Source: Multiple Sclerosis
Satisfaction of Patients Treated with Platinum Derivatives with Antiemetic Therapy
The fixed oral combination of netupitant with palonosetron (NEPA) is used for the prevention of nausea and vomiting induced by cytotoxic chemotherapy. A prospective German study evaluated the benefit…23. 9. 2020 Source: Antiemetic Therapy
Simple antiemetic prophylaxis for breast cancer patients treated with AC chemotherapy
The combination of an anthracycline cytostatic agent with cyclophosphamide (AC) is among the highly effective chemotherapy regimens for breast cancer. Individually, these cytostatic agents carry a…23. 9. 2020 Source: Antiemetic Therapy
Observational Study of Pegylated rVIII Administration in Real Clinical Practice
A recently published article by American hematologists provided valuable information about the treatment with pegylated recombinant factor VIII (rVIII) in real clinical practice. This is the most…21. 9. 2020 Source: Hemophilia
Cost-effectiveness in Bleeding Control for Acquired Hemophilia A
A pharmacoeconomic analysis showed favorable cost-effectiveness of activated prothrombin complex concentrate in the indication of bleeding control in patients with acquired hemophilia A.18. 9. 2020 Source: Hemophilia
Comparison of Efficacy of Bisoprolol and Metoprolol ZOK in Patients with Mild to Moderate Hypertension – Results of the CREATIVE Study
Suppression of increased activity in the sympathoadrenal system is currently one of the main goals of antihypertensive therapy. Beta-blockers play an important role in regulating the sympathetic…17. 9. 2020 Source: Cardiovascular Continuum
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