Prognostic and predictive factors in prostate cancer
Prognostické a prediktívne faktory karcinomu prostaty
Karcinom prostaty je jednou z hlavných příčin morbidity a mortality na zhubne nádory u mužov. Aj napriek pokrokom v jeho diagnostike a liečbe sa nezaznamenal výraznější pokles v úmrtnosti. Preto sa súčasné vědecké výskumy zameriavajú na Madame prognostických faktorov, ktoré by mohli predpovedať vývoj ochorenia pacientov. Mnoho klinicky významných prediktívnych faktorov karcinomu prostaty vychádza z vyšetrenia vzorky tkaniva patológom. Podlá Kolegia amerických patológov (CAP) sú prognostické a prediktívne faktory zatriedené do troch hlavných kategorií. Autor článku popisuje jednotlivé faktory v týchto skupinách. Zdórazňuje nutnost analyzovat a študovat ďalšie nové biomarkery za účelom lepšieho individuálneho managementu a liečby pacientov.
Kľúčové slova:
prognostické a prediktívne faktory, karcinom prostaty
Authors:
V. Bartoš
Authors‘ workplace:
Ústav patologickej anatomie Jesseniovej lekárskej fakulty a Martinskej fakultnej nemocnice v Martine, Kollárova 2, 036 59, Martin Přednosta: prof. MUDr. Plank Lukáš CSc.
Published in:
Prakt. Lék. 2006; 86(4): 193-195
Category:
Of different specialties
Overview
Prostate cancer is a leading cause of morbidity and mortality in men. Despite advances in detection and treatment, there has been no significant decrease in mortality. Therefore, recent research effort has gone into the finding of the prognostic factors that can predict outcome in patients. Many of the clinically important predictive factors in prostate cancers are derived from a pathologist‘s examination of tissue specimens. According to College of American Pathologists (CAP), prognostic and predictive factors are stratified into three main categories. The author of the article describes individual factors included in these groups. He stress necessity to study and analyse other new biomarkers for better management and treatment in individual patients.
Key words:
prognostic and predictive factors, prostate cancer
Labels
General practitioner for children and adolescents General practitioner for adultsArticle was published in
General Practitioner
2006 Issue 4
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