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Comparable Long-term Safety of Tofacitinib and Biologics in RA Treatment – Data from a US Registry

18. 11. 2021 Source: Arthritis

An analysis of the long-term safety profile of tofacitinib in real clinical practice was published in the journal of the American College of Rheumatology (ACR). Patients with rheumatoid arthritis (RA) who started treatment with tofacitinib showed a similar frequency of predefined adverse events of special interest compared to a cohort treated with biological disease-modifying antirheumatic drugs (bDMARDs).

Webinář SGLT2i v ESC HF Guidelines vs. reálná praxe

Webinar SGLT2i in ESC HF Guidelines vs. Real Practice

Dear Doctor, Boehringer Ingelheim, in collaboration with the 2nd Department of Internal Medicine -…
18. 11. 2021 Source: Anticoagulant Treatment
Echokardiografie_srdce_monitoring_kardiomyopatie_angina_pectoris_septum_venózní_hypertenze

Mechanisms of Cardioprotective Effects of SGLT2 Inhibitors

Inhibitors of sodium-glucose cotransporter 2 (SGLT2i, gliflozins) are a relatively new group of…
18. 11. 2021 Source: Heart Failure
doktorka_dite_leukemia

Summary of Guidelines for the Diagnosis, Prevention, and Treatment of Invasive Fungal Infections in Pediatric Patients with Leukemia and Post Hematopoietic Stem Cell Transplantation

Invasive fungal diseases are a significant cause of morbidity and mortality among immunocompromised…
18. 11. 2021 Source: Anti-Infectives
farmacie_antibiotika_tablety_kapsle_pilulky

Basic Cardiovascular Benefits of the Oral Antidiabetic Medication Empagliflozin

Type 2 diabetes mellitus is one of the main risk factors for cardiovascular (CV) diseases.…
18. 11. 2021 Source: Heart Failure
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Reversal of Dabigatran Effects with Idarucizumab in Patients Requiring Urgent Procedures: Subanalysis of the RE-VERSE AD Study

The effect of idarucizumab as a reversal agent in patients treated with dabigatran in situations…
18. 11. 2021 Source: Anticoagulant Treatment
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Safety of Dabigatran According to a Meta-Analysis of 7 Randomized Controlled Trials

Dabigatran is a direct thrombin inhibitor from the group of direct oral anticoagulants (DOACs),…
18. 11. 2021 Source: Anticoagulant Treatment
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Efficacy and Safety of Dual Bronchodilator Therapy for COPD – From Randomized Clinical Trials to Real-World Clinical Practice

Dual bronchodilator therapy (LAMA + LABA) represents one of the mainstays of treating chronic…
18. 11. 2021 Source: Treatment of Asthma and COPD
kapka krve cukr srdce cukrovka diabetes srdeční

Epidemiology, Pathophysiology, Diagnosis, and Treatment of Heart Failure in Patients with Diabetes

The proven benefit of one class of antidiabetic drugs – sodium-glucose cotransporter 2 inhibitors…
18. 11. 2021 Source: Cardiovascular Continuum
štítná žláza_léky_stetoskop

Subclinical Hypothyroidism Associated with the Use of Allopurinol? What the Results of a Large Multicenter Study Suggested

Allopurinol is a widely used drug for the treatment of hyperuricemia and gout. The retrospective…
18. 11. 2021 Source: Thyroid Disorders
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