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Adding Paracetamol to Tramadol to Relieve Early Postoperative Pain After Lumbar Discectomy

4. 12. 2020 Source: Pharmacotherapy of Pain

A recently published study is likely the first prospective randomized controlled trial comparing the postoperative analgesic efficacy of a tramadol and paracetamol combination versus tramadol alone. Its results favor the combination, with significantly lower pain scores during the first 30 minutes and reduced tramadol consumption within the first 24 hours post-surgery.

Prediction of Ischemic Stroke Risk in Patients with Rheumatoid Arthritis Using a Simplified Score

Ischemic strokes (iCMP) are a common cause of death or significant disability in developed countries. Patients with rheumatoid arthritis (RA) are affected by them even more frequently than the…

3. 12. 2020 Source: Arthritis

The Wound Healing Process Step by Step and What Can Complicate It

Proper care of injuries is a fundamental prerequisite for their successful healing. Knowing the individual phases of healing facilitates treatment and helps prevent the most common complications.

2. 12. 2020 Source: Wound Healing

Hope Awakens with Early Diagnosis of Parkinson's Disease Based on Skin Odor

According to scientists from the United Kingdom, a simple test based on an individual's skin odor could aid the early diagnosis of Parkinson's disease. A study has already been launched to investigate...

2. 12. 2020 Source: Parkinson's Disease

Deep stimulation of the globus pallidus improved clinical symptoms in a patient with refractory parkinsonism and genetic mutation

The authors of the presented work studied the effects of deep brain stimulation (DBS) in a patient with Parkinson's disease with a genetic mutation that manifests in early adulthood.

2. 12. 2020 Source: Parkinson's Disease

ADCT –⁠ a simple tool for self-diagnosis of patients with severe atopic dermatitis

Atopic dermatitis (AD) is a chronic inflammatory disease not only of childhood. It can negatively affect the quality of life despite being treatable. Control and management of the disease in…

1. 12. 2020 Source: Systemic treatment of atopic dermatitis, asthma, and chronic rhinosinusitis with nasal polyposis – Type 2 inflammation

Dupilumab in the Treatment of Adolescent Patients with Severe and Refractory Atopic Dermatitis

An open multicenter study evaluating dupilumab in the treatment of moderate to severe atopic dermatitis in adolescents confirmed its long-term efficacy and safety in this age group. In addition to…

1. 12. 2020 Source: Systemic treatment of atopic dermatitis, asthma, and chronic rhinosinusitis with nasal polyposis – Type 2 inflammation

Noonan's Syndrome –⁠ History and Present

The genetically determined syndrome linking congenital heart defect with a typical facial phenotype is named after Jacqueline Noonan, a pediatric cardiologist who practiced in the second half of the…

30. 11. 2020 Source: Growth Disorders

Register of Patients Treated with Growth Hormone (REPAR): Data Analysis as a Path to Further Optimization of Care

Treatment with recombinant growth hormone (rhGH) is available in the Czech Republic for all children meeting the indication criteria. A network of 10 centers covers the entire country, and all…

30. 11. 2020 Source: Growth Disorders

Does Ixekizumab Have Long-term Effects on Improving Psoriatic Arthritis Symptoms?

The extension of the SPIRIT-P2 study brought results of ixekizumab in patients with psoriatic arthritis (PsA) after 3 years of use. The data below were presented as a poster presentation at the…

30. 11. 2020 Source: Biological Treatment

View on the Treatment of Rheumatoid Arthritis with Baricitinib Using the NNT Indicator

Clinical parameters assessed by patients themselves are an important tool in evaluating the effectiveness of new drugs and are particularly significant in the evaluation of treatments for chronic…

30. 11. 2020 Source: Biological Treatment

Shared Decision-Making on Kidney Function Replacement

Peritoneal dialysis (PD) is not a new development, but its significance is becoming increasingly recognized. Until recently, we may not have fully appreciated its value, but in light of the global…

30. 11. 2020 Source: Chronic Kidney Disease

Options for Modifying and Improving the Efficiency of the HJHS Scoring System

The Hemophilia Joint Health Score (HJHS) is a validated tool for assessing joint health in individuals with hemophilia. Can it be modified to be used more effectively in clinical practice?

30. 11. 2020 Source: Hemophilia with Movement

Physiotherapy as Part of Comprehensive Care for People with Hemophilia –⁠ Recommendations vs. Reality

It appears that the physiotherapeutic care provided in reality to people with hemophilia does not align with current recommendations, which see it as an integral part of a multidisciplinary approach.…

30. 11. 2020 Source: Hemophilia with Movement

Use of Brodalumab in the Treatment of Severe Plaque Psoriasis −⁠ Case Report

The case report by MUDr. Jan Šternberský, Ph.D., from the Clinic of Skin and Venereal Diseases, UP Faculty of Medicine and University Hospital Olomouc, demonstrates the excellent effect of brodalumab…

28. 11. 2020 Source: Topical Treatment of Psoriasis

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