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Efficacy and Safety of Gefitinib in Combination with Chemotherapy vs. Chemotherapy Alone in the Treatment of Advanced NSCLC

15. 10. 2021 Source: Oncological Treatment

Non-small cell lung cancer (NSCLC) remains a disease with high mortality. The meta-analysis presented below compared the efficacy and safety of gefitinib in combination with chemotherapy versus chemotherapy alone in the treatment of advanced NSCLC.

Nasal Smear as a Modern and Gentle Diagnostic Method for Allergic Rhinitis

Up to 130 million Europeans suffer from allergic rhinitis. Until now, standard diagnostic methods have been skin prick tests and laboratory blood tests. Both methods, however, present significant…

14. 10. 2021 Source: Allergic Reactions

Physiological and Clinical Effect of Romiplostim in the Treatment of ITP

Romiplostim in the treatment of immune thrombocytopenia (ITP) has demonstrated safety and the promise of long-term remission, enabling many pediatric and adult patients to discontinue treatment and…

11. 10. 2021 Source: Immune Thrombocytopenia

Administration of Romiplostim in Patients with ITP in Real-World Practice in Central Europe

Data from the PLATON study on the administration of romiplostim in real-world clinical practice in Central and Eastern Europe confirmed very good efficacy in patients with newly diagnosed,…

11. 10. 2021 Source: Immune Thrombocytopenia

Vaccination Against COVID-19 in Patients Treated With Anticoagulants

Canadian professional societies and the National Health Service (NHS) in the United Kingdom recommend COVID-19 vaccination even for patients treated with anticoagulants. The benefit of vaccination in…

11. 10. 2021 Source: Anticoagulant Treatment

Importance of Testing for Iron Deficiency in Patients with Chronic Heart Failure and Treatment Options

Intravenous iron application in patients with heart failure and iron deficiency is now part of ESC guidelines aimed at improving symptoms, increasing exercise tolerance and quality of life in these…

5. 10. 2021 Source: Iron Deficiency and Anemia

Effects of Metformin on the Cardiovascular System of Patients with Diabetes, but Also Without It

Diabetes mellitus (DM) is considered an independent risk factor for the development of ischemic heart disease (IHD). The prevalence of IHD is continuously increasing, making early detection of risk…

5. 10. 2021 Source: Modern Treatment of Diabetes

Recommendations for Lipid Administration in Patients on Home Parenteral Therapy

Home parenteral therapy is an important part of treatment for patients with chronic intestinal failure who cannot achieve adequate nutrition through enteral feeding. An integral component of this…

4. 10. 2021 Source: Parenteral Nutrition

No deficiency of essential fatty acids in home parenteral nutrition

A Dutch-British study, the results of which were published in the Journal of Parenteral and Enteral Nutrition, addressed the issue of potential deficiency of essential fatty acids in patients using…

4. 10. 2021 Source: Parenteral Nutrition

Does Administration of Saline Make a Crucial Difference Compared to Balanced Crystalloids in Critically Ill Patients?

A study published in the New England Journal of Medicine provided data on mortality and deterioration of renal function in adult patients in intensive care units, depending on whether they received…

4. 10. 2021 Source: Parenteral Nutrition

Nutritional Therapy for Critically Ill Patients in the ICU –⁠ Current Recommendations

Critically ill patients hospitalized in the intensive care unit (ICU) require nutritional support to maintain adequate energy intake. Only by doing so can their clinical condition be prevented from…

4. 10. 2021 Source: Parenteral Nutrition

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Efficacy and Safety of Enoxaparin as Bridging Anticoagulant Therapy After Ventricular Assist Device Implantation

The implantation of a ventricular assist device has become an increasingly common method in the treatment of end-stage heart failure in recent years. The implantation of the device necessitates…

1. 10. 2021 Source: Thromboprophylaxis

Administration of Low-Molecular-Weight Heparin After Hemorrhagic Stroke: What Is the Appropriate Timing?

Hemorrhagic stroke (HS) is a condition that raises doubts and concerns about anticoagulation. Is early prevention of thromboembolic complications appropriate?

30. 9. 2021 Source: Thromboprophylaxis

muž kašel rouška astma muž kašle do roušky covid

Asthma and Prognosis of Patients with COVID-19

The impact of asthma, its severity, and treatment on the prognosis of patients infected with the SARS-CoV-2 coronavirus was examined in an observational study published this spring.

23. 9. 2021 Source: Asthma under control

Patient with Moderate Hemophilia A and Development of FVIII Inhibitor in Old Age and Atrial Fibrillation −⁠ Interactive Case Study

MUDr. Petr Smejkal, Ph.D., from the Department of Clinical Hematology, FN Brno, has prepared a case study for you of a patient born in 1941, diagnosed with hemophilia A at around 10 years of age. In 2013,...

22. 9. 2021 Source: Quality Life Even with Hemophilia

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