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When You Say Amyloid…
12. 12. 2022 Source: AmyloidosisThe term 'amyloid' was first used by the German doctor Rudolf Virchow in the mid-19th century. He described it as a pathological substance which he originally thought was starch. Although it was quickly discovered that it was a substance of protein nature, the reference to starch (from the Greek amylon) remained in the name.
Practical Experiences Using ZULP in Cardiology
The application of a product containing ferric carboxymaltose (FCM) or the use of a contrast agent with sulfur hexafluoride in microbubbles are examples of the use of specially accounted medicinal…12. 12. 2022 Source: Chronic Heart Failure and Lipidology
How Will the New Player in Dyslipidemia Therapy Change the "Rules of the Game"?
Inclisiran, as an innovative drug indicated for adult patients with primary hypercholesterolemia or mixed dyslipidemia, was registered in the European Union at the end of 2020. Internists and…12. 12. 2022 Source: Chronic Heart Failure and Lipidology
Undiagnosed Hereditary Angioedema in Pregnancy – Case Study
Delayed diagnosis or misdiagnosis is not uncommon with hereditary angioedema (HAE), especially during pregnancy and the postpartum period. A case study by Canadian authors illustrates that HAE should…8. 12. 2022 Source: Hereditary Angioedema
Successful Long-Term Subcutaneous Prophylaxis of Hereditary Angioedema – Case Study
Hereditary angioedema (HAE), arising from a deficiency of C1 inhibitor (C1-INH), clinically manifests as swelling of the subcutaneous tissue and mucous membranes. The standard prophylactic therapy…8. 12. 2022 Source: Hereditary Angioedema
Biochemotherapy of Aggressive Rectal Carcinoma – A Case Study from the Czech Republic
Colorectal cancer arises from a complex interplay of environmental and lifestyle factors complemented by hereditary factors. Nowadays, it represents not only a health concern but also a socioeconomic…7. 12. 2022 Source: Colorectal Cancer
Incidence of Secondary Malignancies in CLL Patients on FCR Regimen in Central Europe
Chronic lymphocytic leukemia (CLL) represents the most common type of leukemia in Western countries with closely related incidence in Central European states. Since 2000, new therapeutic regimens…7. 12. 2022 Source: Chronic Lymphocytic Leukemia
Pathogenetic Mechanisms Underlying the Development and Progression of Interstitial Lung Diseases
Interstitial lung processes (ILP) represent an umbrella term for a wide range of nosological units that differ from each other in clinical course, prognosis, and pathogenesis. Most ILPs are…6. 12. 2022 Source: Progressive Interstitial Pulmonary Processes
Finding Balance Between Intracranial Efficacy and Adverse Effects of ALK Kinase Inhibition
More than 7 years – that is the current median survival of patients with non-small cell lung cancer (NSCLC) with a mutation in the anaplastic lymphoma kinase (ALK) gene who are receiving targeted…6. 12. 2022 Source: Genetic Profile and Treatment of NSCLC
What did the first data from the pilot lung cancer screening show?
Czech pulmonologists have released the first interim results of this year's pilot testing of heavy smokers due to the risk of lung cancer. More than 4,000 patients passed through the hands of general…5. 12. 2022 Source: MDT Board
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