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Metamizole – wide possibilities of an analgesic with a unique mechanism of action and different routes of administration
Metamizole is a non-addictive pyrazolone analgesic with antipyretic effects, which differs from other non-opioid analgesics by its spasmolytic action. It is indicated in monotherapy and in combinations for the treatment of severe acute and chronic pain. Its high analgesic efficacy is evidenced by a low number of patients needed to treat to achieve at least 50% pain relief in 4-6 hours. The favorable safety profile of metamizole is supported by more than 100 years of clinical experience.
How to vaccinate children against pneumococcus?
Pneumococcus is a dreaded pathogen causing serious diseases in pediatric patients. However, it can…
The Potential of Vinpocetine in the Treatment of Cardiovascular Diseases
Vinpocetine is a nootropic indicated for the symptomatic treatment of cerebral ischemic…
Artificial Intelligence in Breast Cancer Detection – Results from Real Clinical Practice
A study conducted in Sweden examined the use of artificial intelligence (AI) in the detection of…
Efficacy of Luspatercept in 1st Line Treatment of Anemia Due to Low-Risk Myelodysplastic Syndrome
A planned interim analysis of the COMMANDS study showed a greater benefit of the innovative…
HPD 2024: Czech data from real-world practice confirm that mucolytic treatment can reduce COPD exacerbations, even in the future
Chronic obstructive pulmonary disease (COPD) is a global issue. Does it create the same burden…
HPD 2024: Bronchitis as an Early Feature of PreCOPD, Role of Mucus Plugs in COPD, and New Findings on Their Exacerbations
Exacerbations of chronic obstructive pulmonary disease (COPD) significantly affect disease…
Benefit of Oral Semaglutide for Patients with Type 2 Diabetes in the General Practitioner's Office
Oral semaglutide is a modern antidiabetic suitable within primary care for people with type 2 diabetes,...
Targeting HER2 is Clinically Meaningful Even with Its Low Expression
Distinguishing HER2 receptor expression status on the surface of breast cancer tumor cells as…
A device the size of a matchbox will help treat obstructive sleep apnea
Obstructive sleep apnea, also known as sleep apnea syndrome, is the second most common sleep…