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How and when does the reaction to gluten begin in coeliac disease? A new Canadian study offers potential answers
As is well known, coeliac disease is a systemic autoimmune disorder characterised by damage to intestinal epithelial cells (IEC). Canadian researchers have sought to uncover the relationship between intestinal epithelial cells and T lymphocyte activation in this disease. The results of their work provide hope for the potential development of an effective therapy.

Could Artificial Intelligence Help with Emergency Department Triage in the Future?
A new study by researchers from the University of California, San Francisco, is one of the few to…

Results of Prophylactic Treatment of Severe von Willebrand Disease with Recombinant vWF
The phase III study cited below evaluated the efficacy and safety of 12-month prophylaxis with recombinant...

The Brain, Too, Has Its Midlife Crisis. How Do These Changes Relate to the Risk of Dementia in Old Age?
The human brain undergoes rapid changes during certain developmental periods. Childhood,…

Excellent effect of sotorasib in a higher line of treatment in a patient with NSCLC with G12C mutation of KRAS – a case study
We present a case study of an elderly patient with non-small cell lung cancer (NSCLC) treated with…

Fluoroscopically Calibrated 3D-Printed Tools Increase Osteotomy Precision During Tumor Resection Near Joints
The area around the knee is a common site for malignant bone tumors, such as osteosarcomas. Their…

Intermittent Fasting May Carry Significant Health Risks
Results from an observational study presented at this year’s American Heart Association (AHA)…

Smaller Volume and Faster Infusion Rate of aPCC: What Do Current Data Say About This Modification?
Administering an infusion of activated prothrombin complex concentrate (aPCC) at the standardized rate...

Portal Vein Thrombosis as a Complication of COVID-19 Infection – A Case Study
COVID-19 Infection is Associated with a Higher Risk of Thrombotic Complications. Many cases of deep...

Experience with 20% subcutaneous immunoglobulin in the treatment of primary immunodeficiency
Patients with primary antibody deficiency are administered immunoglobulin (Ig) replacement therapy to...