News

Teriflunomide vs. Dimethyl Fumarate: Does Their Classification into Different Treatment Lines Have Merit?
Teriflunomide is one of the first-choice medications in the treatment of multiple sclerosis (MS) patients, not only in the Czech Republic. Conversely, the use of dimethyl fumarate is more limited here compared to other countries. Did the data from real-world clinical practice published this year actually demonstrate differences in the efficacy of both medications, and thus justify their classification?

Prevalence of Heart Failure and Its Subtypes in the Population of Developed Countries
In developed countries, heart failure occurs in approximately 2% of the population, with an annual…

Inclisiran − a new addition to the arsenal of dyslipidemia treatment
At the XXIX Congress of the Czech Society of Internal Medicine ČLS JEP, held November 6−9, 2022 in…

Use of Inclisiran in a Patient in Secondary Cardiovascular Prevention
Lowering LDL cholesterol (LDL-c) is one of the primary goals for reducing cardiovascular (CV) risk…

Cenobamate − A Case Study from Slovak Real Practice
Cenobamate is indicated for adjunctive therapy of focal seizures with or without secondary…

Brigatinib in the Therapy of Pretreated Patients with Advanced ALK-Positive NSCLC
A French study analyzed clinical data of pretreated ALK-positive patients with advanced non-small…

Addition of ixazomib to lenalidomide and dexamethasone in multiple myeloma − Data from real-world Czech practice
A group of Czech and Slovak experts led by Associate Professor Jiří Minařík from the…

Consolidation therapy with brentuximab vedotin after autologous stem cell transplantation in patients with relapsed/refractory Hodgkin lymphoma
At the 12th International Symposium on Hodgkin Lymphoma (ISHL), held in October 2022 in Cologne,…

Role of Transthyretin in the Development of Amyloidosis
Transthyretin (TTR), one of the transport proteins, tends to form extracellular deposits that…

3D Printing is Already Helping with Eye Prostheses: What Benefits Does the Innovation Offer Patients?
Cosmetic eye prostheses, usually made of glass or acrylic, serve to mask cosmetic defects due to…