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Teriflunomide in the Treatment of RRMS: The Best Working Drug Is the One That the Patient Actually Takes
Teriflunomide is an oral disease-modifying drug (DMD) used in the therapy of relapsing-remitting multiple sclerosis (RRMS). The authors of the cited American study assessed adherence to this treatment and subsequently the effect of adherence on the occurrence of RRMS relapses and the utilization of healthcare services during the first year following the initial prescription of teriflunomide.

Early Tumor Regression as a Marker of Overall Survival in First-Line Treatment of mCRC
In the treatment of metastatic colorectal cancer (mCRC), prognostic factors besides overall…

Meta-Analysis of the Results of Studies Comparing the Effectiveness of Manual and Sonic Toothbrushes
Brushing teeth is a fundamental means of maintaining good oral hygiene. While many people still…

Is Obesity a Universal Phenotype in Children with Type 2 Diabetes?
What is the global prevalence of obesity in children and adolescents suffering from type 2 diabetes…

Echocardiography in the Diagnosis of Cardiac Amyloidosis
Cardiac amyloidosis remains a diagnostic challenge that requires great clinical vigilance. The…

Diagnosis and Management of Therapy for a Breastfeeding Patient with Significant Elevation of Liver Enzymes Postpartum – Interactive Case Study
In the following case study, we present a specific approach to a patient who developed a significant...

Empagliflozin will be funded from May for symptomatic heart failure regardless of EF LK value
Empagliflozin entered the market as an antidiabetic drug operating on the principle of reducing…

Current View on Obstacles in Proper Use of Antibiotics and the Role of Biomarkers in Infection Diagnosis
In the fight against antibiotic resistance, principles for the proper use of antibiotics (ATB) have…

Screenings of Lung Cancer and COPD are Significant. What Do the Latest Data from Czechia Say?
At the end of January, an expert seminar was held, focusing on updates in the treatment of…

Measurement of Serum Trough Levels of IgG as an Adequate and Beneficial Indicator for Assessing the Pharmacokinetics of Subcutaneously Administered Products
For many patients with primary immunodeficiency, lifelong immunoglobulin substitution is essential to...