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metastatický karcinom prsu

Trastuzumab Deruxtecan in Patients with HER2+ Metastatic Breast Cancer

12. 3. 2024 Source: Ovarian and Breast Cancer

Last year, results of studies published in the Lancet journal demonstrated a significant clinical benefit of trastuzumab deruxtecan in patients with HER2+ metastatic breast cancer (mBC) pre-treated with anti-HER2 therapy, in the 2nd or later lines of treatment compared to trastuzumab emtansine (DESTINY-Breast03 study, second interim overall survival analysis) and after failure of trastuzumab emtansine compared to physician's choice of therapy (DESTINY-Breast02 study).

CLL

Benefits of Time-Limited CLL Therapy

The advent of new targeted molecules has significantly influenced the possibilities of therapy for…
5. 3. 2024 Source: Chronic Lymphocytic Leukemia
srdce

Improving treatment outcomes of HF with preserved ejection fraction according to JACC: What does the success of gliflozins mean for the future?

The Journal of the American College of Cardiology (JACC) recently issued a scientific statement in…
4. 3. 2024 Source: Heart Failure
úhradové podmínky

Current Reimbursement Conditions for the Dual Inhibitor IL-4/IL-13 Dupilumab

The biologic dupilumab is approved for the treatment of several diseases with type 2 inflammation.…
4. 3. 2024 Source: Systemic treatment of atopic dermatitis, asthma, and chronic rhinosinusitis with nasal polyposis – Type 2 inflammation
mozek

Digital Bridge Between the Brain and Spine: How an Implant Restored Walking Ability to a Paralyzed Patient −⁠ Case Study

When a spinal cord injury occurs, communication between the brain and peripheral nerves is…
4. 3. 2024 Source: medScope.pro
makak

A Cloned Monkey Survived to Adulthood for the First Time. Will We Soon Be Able to Clone Humans?

A macaque named ReTro, born as a result of a cloning experiment by Chinese scientists, has reached…
4. 3. 2024 Source: medScope.pro
zlomenina kost

Can we properly manage osteoporotic fractures?

Osteoporotic fractures are associated with increased morbidity and mortality and often lead to an…
29. 2. 2024 Source: Osteoporosis – Trends in Sequential Therapy
kost

Meta-analysis of the Effectiveness of Romosozumab in the Treatment of Postmenopausal Osteoporosis

Osteoporosis is a prevalent disease with unmet therapeutic needs. Whether the anti-sclerostin…
29. 2. 2024 Source: Osteoporosis – Trends in Sequential Therapy
paranoidní schizofrenie_muž

Lurasidone in a Patient with Paranoid Schizophrenia and Asperger's Syndrome –⁠ A Case Study

Lurasidone is an effective and very gentle antipsychotic which is establishing a prominent position…
27. 2. 2024 Source: Modern Treatment of Schizophrenia
hypotyreózy

Clinical Significance of Smaller Gaps Between Strengths of Levothyroxine Preparations in the Treatment of Hypothyroidism

Many levothyroxine preparations have relatively large intervals between doses (25 µg, 50 µg, and 75…
23. 2. 2024 Source: Thyroid Disorders
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