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News

Safety and Tolerance of Metamizole in Postoperative Analgesia in Children

16. 3. 2020 Source: Analgesia

Due to the potential serious side effects of metamizole, the use of this drug in children is often a topic of discussion. Therefore, a prospective multicenter observational non-interventional post-marketing safety study aimed to evaluate the safety of using metamizole in children, with an emphasis on hemodynamic, anaphylactic, or respiratory reactions and agranulocytosis.

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Type of Pharmacological Thromboprophylaxis and Disease Stage as Risk Factors for Bleeding in Patients After Colorectal Cancer Surgery

Japanese authors of a study published last year in the World Journal of Surgical Oncology attempted…
14. 3. 2020 Source: Thromboprophylaxis
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European Survey on Prophylactic Treatment of Chemotherapy-Induced Nausea and Vomiting Suggests Gaps in Practice and Ways to Improve

Using recommended guidelines for antiemetic prophylaxis can prevent chemotherapy-induced nausea and…
13. 3. 2020 Source: Antiemetic Therapy

New drugs in CLL may also carry specific risks of adverse effects. How to minimize and manage them?

The possibilities for the treatment of chronic lymphocytic leukemia (CLL) have greatly expanded in…
13. 3. 2020 Source: Chronic Lymphocytic Leukemia
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Safety and Efficacy of Different Antithrombotic Regimens in Patients with Atrial Fibrillation after Percutaneous Coronary Intervention

Patients with atrial fibrillation (AF) and acute coronary syndrome (ACS) or after percutaneous…
13. 3. 2020 Source: Anticoagulant Treatment

Treatment of HFrEF with Sacubitril/Valsartan Does Not Have to Be the ‘Last Resort’

The TRANSITION study has provided evidence on the safety and efficacy of administering…
9. 3. 2020 Source: Chronic Heart Failure and Lipidology
medicína_nákres_střevo_střeva_zažívání_kreslené

Could candesartan counteract adverse intestinal changes induced by hypertension?

An experimental study published last year was the first to show that administration of candesartan…
6. 3. 2020 Source: Sartans in the Treatment of Hypertension
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Pharmacokinetics and Safety Profile of Bilastine in Patients Aged 6–11 Years – Findings from Post-hoc Analysis of Studies

The second-generation antihistamine bilastine is approved in Europe for the treatment of allergic…
4. 3. 2020 Source: Allergic Reactions
medicina_zena_zily_tromboza_nohy_doktor_vysetreni

A Brief History of Deep Vein Thrombosis Treatment – From Antiquity to the Present

Deep vein thrombosis is among the common diseases that have accompanied humanity since its…
4. 3. 2020 Source: Prevention of Thrombosis in Surgery
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Current Recommendations of the American Society of Hematology for the Prevention of Thromboembolic Disease and Duration of Prophylaxis in Patients Undergoing Major Surgery

At the end of 2019, new recommendations were published by the American Society of Hematology (ASH)…
4. 3. 2020 Source: Prevention of Thrombosis in Surgery
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