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Patient Evaluation of Durvalumab Treatment Results
The interim analysis results of the PACIFIC study, which monitored the efficacy of durvalumab in the treatment of locally advanced unresectable non-small cell lung cancer (NSCLC), demonstrated a significantly longer progression-free survival (PFS) with this treatment compared to placebo. The following work analyzed one of the secondary objectives of the PACIFIC study − patient-reported outcomes (PRO).
Therapy Change from Adalimumab to Baricitinib in Patients with Rheumatoid Arthritis
The aim of the presented analysis of data from the RA-BEAM study was to evaluate the clinical…
Mechanisms Connecting Diabetes Mellitus and Obesity
Obesity has a close relationship with insulin resistance and diabetes mellitus (DM); weight gain is...
Venotonics in Hemorrhoid Therapy – Results of a Systematic Review
Hemorrhoids are among the most common pathological findings in the anorectal area, and their…
Diosmin and its application in the treatment of venous insufficiency
A number of procedures, including pharmacotherapy, are used in the treatment of chronic venous…
Efficacy and Safety of Gene Therapy Using Adeno-Associated Virus Vector in Patients with Choroideremia
Choroideremia (CHM) is a rare genetically conditioned retinal disease caused by mutations in the…
Results of ATTUNE Total Knee Replacement Implantation – Data from the National Joint Registry for England, Wales, Northern Ireland and the Isle of Man
The ATTUNE knee replacement system was fully introduced into clinical practice in 2013. Since then,…
Young man with nephrotic syndrome and portal vein thrombus successfully treated with edoxaban − case report
Venous thrombosis is one of the main complications of nephrotic syndrome (NS), though it is most…
Options of Anticoagulant Therapy During Pregnancy: Focus on Fondaparinux
The use of most medicinal products is limited during pregnancy either by known teratogenic effects…
Alternative to benzodiazepines or clomethiazole in the treatment of alcohol withdrawal syndrome?
Alcohol withdrawal syndrome (AWS) is a potentially life-threatening condition. A meta-analysis…