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Pregabalin in Seniors Confirmed Its Safety and Effectiveness

25. 6. 2020 Source: Neuropathic Pain

A pooled analysis of 11 studies investigated the safety and effectiveness of pregabalin in seniors with neuropathic pain. Are the outcomes in these indicators different for older individuals than in the general population sample?

Induction vs. Escalation Treatment: Which Strategy to Choose in the Therapy of Multiple Sclerosis?

Opinions on the optimal therapy for multiple sclerosis (MS) are constantly evolving, and experts are debating the most appropriate first-line treatment strategy. A British cohort study focused on the…

25. 6. 2020 Source: Multiple Sclerosis

Brodalumab in the Treatment of Psoriasis Symptoms on the Scalp and Nails

A post-hoc analysis of 3 clinical studies (AMAGINE-1/-2/-3) evaluates the effect of treatment with brodalumab or ustekinumab (compared to placebo) in patients with mild to severe psoriasis on the…

24. 6. 2020 Source: Topical Treatment of Psoriasis

IPFchecker Project Helps Detect Patients with Idiopathic Pulmonary Fibrosis

Idiopathic pulmonary fibrosis is a serious progressive disease of the lung tissue of unclear etiology. Highly effective antifibrotic therapy is used in treatment, which can significantly prolong the…

24. 6. 2020 Source: Pulmonary Fibrosis

Options for Anticoagulant Therapy During Catheter Ablation for Atrial Fibrillation: Safety and Efficiency of Bridging with Dabigatran Compared to Interruption of NOACs

Catheter ablation is an established method for treating supraventricular and ventricular arrhythmias. Patients with atrial fibrillation should also use anticoagulant therapy to prevent thromboembolic…

23. 6. 2020 Source: Anticoagulant Treatment

Žena s manikúrou si měří glukometrem inzulin

Prokinetics in the Treatment of Diabetic Gastroparesis

One of the common complications of diabetes mellitus is a motility disorder of the gastrointestinal tract, which can affect any part of the digestive tube, and therefore has various forms. Among…

22. 6. 2020 Source: Gastrointestinal Treatment

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Pregabalin can be chosen as the 1st line treatment for postherpetic neuralgia

The efficacy of pregabalin in patients with postherpetic neuralgia has been demonstrated in 4 multicenter randomized double-blind placebo-controlled studies.

22. 6. 2020 Source: Neuropathic Pain

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Effect of Trifluridine/Tipiracil Combination Depending on Patient Prognosis

The results of the RECOURSE clinical study were published in 2015 and became an important basis for the approval of the trifluridine/tipiracil combination in the treatment of metastatic colorectal…

19. 6. 2020 Source: Treatment of Gastrointestinal Carcinomas

Impact of Vitamin D Deficiency on Inflammatory Cytokine Concentrations in Patients with Diabetic Foot Syndrome

Vitamin D deficiency is relatively common in the population. Vitamin D plays an important role, among other things, in the functioning of the immune system. The aim of the presented study was to determine...

18. 6. 2020 Source: Wound Healing

žena lékařka doktorka konzultace špatné zprávy

Treatment with Osimertinib in Patients with NSCLC After Disease Progression on Previous Therapy –⁠ Case Study

We present a case study of a patient with non-small cell lung cancer (NSCLC) with a proven activating mutation of the epidermal growth factor receptor (EGFR) gene, who developed resistance to the…

16. 6. 2020 Source: Lung Cancer

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