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Diosmin and Hesperidin: What Does Pharmacokinetics Show?
Flavonoids are plant-derived compounds that have a number of beneficial pharmacological effects. Among the most well-known flavonoids, alongside rutin, are diosmin and hesperidin, which are used as venotonics and vasoprotectives in chronic venous insufficiency (CVI).
Obinutuzumab and Early Progression of Patients with Previously Untreated Follicular Lymphoma − Analysis of Data from the GALLIUM Study
The GALLIUM study demonstrated longer progression-free survival (PFS) in patients with previously…
Impact of Dabigatran and Warfarin Treatment on the Risk of Acute Kidney Injury in Patients with Atrial Fibrillation
What clinical characteristics in patients with non-valvular atrial fibrillation may indicate a…
High-Dose Cyclophosphamide in Hard-to-Treat Patients with B-NHL
For hard-to-treat patients with non-Hodgkin lymphoma, cyclophosphamide administered in one or two…
Boy with Hemophilia A with Inhibitor − Case Study with Voting
Presented by: Assoc. Prof. MUDr. Jan Blatný, Ph.D., Department of Pediatric Hematology, University Hospital...
Efficacy of Combination Therapy for Chronic Lymphocytic Leukemia in Patients with Complex Karyotype
A complex karyotype (presence of ≥ 3 chromosomal abnormalities) is a negative prognostic marker in…
Role of Chemoimmunotherapy in the Era of Rapid Development of CLL Treatment Strategies and Emergence of New Drugs
In the context of the significant advancements in the field of immunotherapy and evidence of its…
Recommendations for the diagnosis of ITP in adults and children according to ASH guidelines
The American Society of Hematology (ASH) guidelines from 2019 highlighted several important aspects…
Current ASH Guidelines on ITP Management 2019 – Recommendations for Newly Diagnosed ITP in Children
At the end of 2019, the American Society of Hematology (ASH) published current guidelines for…
Clinical Results of the Pinnacle Acetabular System: Data from the UK Joint Replacement Registry
The Pinnacle Acetabular System has been available on the market for nearly two decades. Since then,…