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Evaluation of the m7-FLIPI score in patients with follicular lymphoma revealed a promising predictive biomarker for determining suitable chemotherapy

27. 1. 2020 Source: Non-Hodgkin Lymphomas and CLL

The authors of a study presented at the December congress of the American Society of Hematology (ASH) in Orlando introduced a new prognostic tool, m7-FLIPI, for determining the risk level of patients with follicular lymphoma (FL). They tested its utility using samples from the GALLIUM clinical trial and, during the analysis, discovered a promising biomarker that could help in selecting the primary chemotherapy for FL patients.

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Kadcyla in a New Indication –⁠ Adjuvant Therapy for Early HER2+ Breast Cancer

In December, the European Commission approved the expansion of the indication for Roche's medicinal product Kadcyla, which contains the active substance trastuzumab emtansine. This expansion makes…
23. 1. 2020 Source: Breast Carcinoma

Comparison of Safety and Efficacy of Oral and Intravenous Administration of Combination NEPA in the Prophylaxis of Chemotherapy-Induced Nausea and Vomiting

Both oral and intravenous administration of a combination of netupitant (a neurokinin 1 receptor antagonist −⁠ NK1RA) with palonosetron (a 5-HT3 receptor antagonist) offer prevention of…
20. 1. 2020 Source: Antiemetic Therapy

Cost Effectiveness of Netupitant/Palonosetron Combination in the Prophylaxis of Chemotherapy-Induced Nausea and Vomiting

A recently published study compared the costs of achieving a complete response to antiemetic therapy in the prophylaxis of chemotherapy-induced nausea and vomiting (CINV) when using a combination of…
20. 1. 2020 Source: Antiemetic Therapy
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Impact of Oral Antidiabetics on Heart Failure

Diabetes mellitus is primarily perceived as a risk factor for ischemic heart disease and general atherosclerotic complications. However, an equally significant problem is the association between diabetes...
19. 1. 2020 Source: Diabetes
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Position of Levodropropizine in Cough Therapy

An international group of specialists focused in 2016–2017 on a detailed evaluation of current options for cough therapy. The authors based their analysis on individually prepared reviews using…
15. 1. 2020 Source: Cough Therapy

Cost Effectiveness of FVIII Substitution Versus Non-Factor Therapy for Hemophilia A

With new treatment options for hemophilia A without inhibitors, the question of cost-effectiveness of different treatment approaches arises. The results of a model comparing replacement therapy and…
15. 1. 2020 Source: Hemophilia
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The World of Viruses is Constantly Evolving and Bringing Us New Surprises

The last decade has been marked by the emergence of new, as well as re-emerging human pathogens responsible for various infectious diseases. Viruses, especially those of zoonotic origin that originate...
13. 1. 2020 Source: Anti-Infectives
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Vascular Disease in the Gradually Aging Population of Hemophiliacs: An Underestimated Problem?

The aging population of individuals with hemophilia brings new experiences and challenges, leading to the search for the safest and most effective treatments and prevention strategies for diseases…
10. 1. 2020 Source: Hemophilia
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Less Ventricular Arrhythmias and ICD Shocks After Introduction of Sacubitril/Valsartan

Is the decrease in the incidence of sudden cardiac death among patients using sacubitril/valsartan due to a lower risk of ventricular arrhythmias? And does it have anything to do with reverse left…
8. 1. 2020 Source: Chronic Heart Failure and Lipidology
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Diosmin –⁠ Still an Important Modality in the Treatment of Venous Insufficiency

Chronic venous insufficiency is a highly prevalent disease in the Western population. Unfortunately, it remains without causal treatment. In the recommended therapeutic procedures, especially in the initial...
3. 1. 2020 Source: Venous Insufficiency
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Europe and Tooth Decay: The Situation is Improving Thanks to Fluorides and New Technologies

How to prevent tooth decay? This question has been addressed by doctors for several centuries. A major breakthrough occurred in the 1960s when the effect of fluorides was discovered. However, the…
1. 1. 2020 Source: Dental Caries
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