Immunophenotyping of childhood leukaemias
Imunofenotypizace dětských leukemií
Imunofenotypizace je již dnes standardní metodou v diagnostice hemato-onkologických onemocnění. V současné době zažíváme rozvoj mnohobarevné průtokové cytometrie, jak ve výzkumu, tak i v klinické diagnostice. Práce shrnuje diagnostiku a sledování akutní lymfoblastické leukemie pomocí průtokové cytometrie.
Klíčová slova:
imunofenotypizace, mnohobarevná průtoková cytometrie, akutní leukemie, expresní profilování, minimální reziduální nemoc
Authors:
T. Kalina 1,2,3; E. Mejstříková 1,2,3; M. Vášková 1,2,3; O. Hrušák 1,2,3
Authors‘ workplace:
Ústav imunologie, 2Klinika dětské hematologie a onkologie UK 2. LF a FN Motol, 3CLIP Childhood Leukemia
Investigation Prague
1
Published in:
Transfuze Hematol. dnes,12, 2006, No. 1, p. 20-25.
Category:
Comprehensive Reports, Original Papers, Case Reports
Overview
Immunophenotyping is a standard method used in diagnostics of hematological malignancies. Progress in number of multicolour cytometry as well as new targets identified by genomics bring new possibilities in research and diagnostics. These aspects are summarized in the article.
Key words:
immunophenotyping, multicolour flow cytometry, acute leukaemia, expression profiling, minimal residual disease
Labels
Haematology Internal medicine Clinical oncologyArticle was published in
Transfusion and Haematology Today
2006 Issue 1
- The Benefit of Liposomal Irinotecan in the Treatment of Pancreatic Cancer in a Young Patient – A Case Study
- Definition and Classification of Chronic Kidney Disease According to KDIGO
- Doc. Jiří Kubeš: The major benefit of proton therapy lies in protecting healthy tissues
- Minimally Invasive Treatment of Pilonidal Sinus: Laser and Negative Pressure Therapy as a Gentle and Effective Modality
Most read in this issue
- Real cost of chronic myeloid leukemia treatment with nonmyeloablative hematopoietic stem cell transplantation and comparison with cost of hypothetical imatinib treatment. What shall be considered in the cases of extremely costly medical procedures?
- Transmission of prion disease by blood and hot news in detection methods of abnormal prion protein
- Immunophenotyping of childhood leukaemias
- Plasmatic concentration of soluble endoglin in patients with lymphoid malignancies