Acute exacerbation of chronic obstructive pulmonary disease as seen by the intensivist
Authors:
R. Zazula; A. Spálený
Authors‘ workplace:
Anesteziologicko-resuscitační klinika 1. lékařské fakulty
a Fakultní Thomayerovy nemocnice
; Přednosta: MUDr. Roman Zazula Ph. D.
; Univerzita Karlova v Praze
Published in:
Prakt. Lék. 2008; 88(8): 437-442
Category:
Reviews
Overview
Chronic obstructive pulmonary disease (COPD) is a major cause of mortality and chronic morbidity throughout the world; currently it is the fourth leading cause of death worldwide. The most common causes of acute COPD exacerbation, a frequent reason for hospital admission, include tracheobronchial tree infection, climatic changes, and patient non-compliance. This review outlines the basic pathophysiological characteristics of COPD exacerbation and indication criteria for patient hospitalization in a routine care ward or an ICU. Principles of comprehensive conservative therapy and strategies of invasive and non-invasive ventilatory support are outlined, including current concepts of a potential reduction of respiratory work by administering a mixture of helium and oxygen (heliox) in acute respiratory failure.
Key words:
COPD, respiratory insufficiency, mechanical ventilation, heliox.
Sources
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Labels
General practitioner for children and adolescents General practitioner for adultsArticle was published in
General Practitioner
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