A brief review of radiotherapy of rectal cancer
Authors:
M. Foldyna; E. Voršilková; T. Büchler; J. Abrahámová
Authors‘ workplace:
Fakultní Thomayerova nemocnice s poliklinikou, Praha
; Primář: Prof. MUDr. Jitka Abrahámová, DrSc.
; Onkologické oddělení
Published in:
Prakt. Lék. 2008; 88(12): 718-721
Category:
Of different specialties
Overview
Radiotherapy is an effective method in the treatment of rectal cancer. Preoperative radiotherapy decreases the risk of local recurrence and prolongs overall survival by about 10 %. There is no evidence that postoperative radiotherapy prolongs survival. Whether radiochemotherapy is more efficient than radiotherapy alone is not clear, since the results of small randomised trials are partly conflicting. Palliative radiotherapy of inoperable rectal cancer offers significant clinical benefit.
Key words:
rectal cancer, radiotherapy, radiochemotherapy.
Sources
1. Glimelius, B., Grönberg, H., Järhult, J., et al. A systematic overview of radiation therapy effects in rectal cancer. Acta Oncol. 2003, 42(5-6), p. 476-492.
2. Glynne-Jones, R., Harrison, M. Locally advanced rectal cancer: what is the evidence for induction chemoradiation? Oncologist 2007, 12(11), p. 1309-1318.
3. Doleželová, H., Ondrová, B., Šlampa, P. Standard radioterapie karcinomů konečníku. Dostupné na WWW: http://www.srobf.cz/cz/StandardyRT/
4. Gunderson, L.L., Russell, A.H., Llewellyn, H.J. et al. Treatment planning for colorectal cancer. Int. J. Radiat. Oncol. Biol. Phys. 1985, 11, p. 1379-1393.
5. Minsky, B.D., Cohen, A.M. Minimising the toxicity of pelvic radiation therapy. Oncology 1988, 2, p. 21-25, 28-29.
6. Shanahan, T.G., Mehta, M.P., Bertelrud, K.L. et al. Minimization of small bowel volumes within treatment fields using customized „belly boards“. Int. J. Radiat. Oncol. Biol. Phys. 1990, 19, p. 469-476.
7. Crane, C.H., Janjan, N.A., Abbruzzese, J.L. et al. Effective pelvic symptom control using initial chemoradiation without colostomy in metastatic rectal cancer. Int. J. Radiat. Oncol. Biol. Phys. 2001, 49, p. 107-116.
8. Brierley, J.D., Cummings. B.J., Wong, C.S. et al. Adenocarcinoma of the rectum treated by radical external radiation therapy. Int. J. Radiat. Oncol. Biol. Phys. 1995, 31, p. 255-259.
9. Lingareddy, V., Ahmad, N.R., Mohiuddin ,M. Palliative reirradiation for recurrent rectal cancer. Int. J. Radiat. Oncol. Biol. Phys. 1997, 38, p. 785-790.
10. Valentini, V., Morganti, A.G., Gambacorta, M.A. et al. Study Group for Therapies of Rectal Malignancies (STORM). Preoperative hyperfractionated chemoradiation for locally recurrent rectal cancer in patients previously irradiated to the pelvis: A multicentric phase II study. Int. J. Radiat. Oncol. Biol. Phys. 2006, 15, 64(4), p. 1129-1139.
Labels
General practitioner for children and adolescents General practitioner for adultsArticle was published in
General Practitioner
2008 Issue 12
- Definition and Classification of Chronic Kidney Disease According to KDIGO
- Doc. Jiří Kubeš: The major benefit of proton therapy lies in protecting healthy tissues
- Minimally Invasive Treatment of Pilonidal Sinus: Laser and Negative Pressure Therapy as a Gentle and Effective Modality
- Trazodone as an Effective Medicine in the Therapy of Depression and Insomnia
- Diagnosis of Cow Milk Protein Allergy − Current Methods and Their Diagnostic Value
Most read in this issue
- Percutaneous endoscopic gastrostomy – experience of one PEG centre in years 2002–2008
- Contemporary approaches to osteosynthesis of child fractures
- Idiopathic thrombocytopenic purpura
- Sigmoid volvulus – untypical condition in childhood