Thyroid cancer and malignant lymphoma – is there a relationship?
Karcinom štítné žlázy a lymfom – existují souvislosti?
V článku jsou popsány případy dvou pacientek, které během svého života onemocněly karcinomem štítné žlázy a lymfomem.
U první nemocné byla nejdříve diagnostikována kožní forma nehodgkinského lymfomu v levé mammě. Kromě kvadrantektomie byla pacientka ozářena celkovou dávkou 40 Gy. Po 7 letech se objevil karcinom štítné žlázy pravděpodobně radiogenního původu. Byla provedena totální tyreoidectomie (TTE) a následovala terapie radiojódem. Obě maligní onemocnění jsou v dlouhodobé remisi.
U druhé pacientky byl nejdříve zachycen karcinom štítné žlázy. Provedením konvenčního léčebného postupu (TTE, radiojód) bylo dosaženo dlouhodobé remise. Po 8 letech vznikl na krku uzlinový syndrom jako projev druhé malignity – Hodgkinského lymfomu. Hematologickému onemocnění pacientka za necelé dva roky podlehla.
Klíčová slova:
karcinom štítné žlázy, Hodkginův lymfom, nehodkginský lymfom.
Authors:
P. Pačesová
Authors‘ workplace:
Ředitel: doc. MUDr. Vojtěch Hainer, CSc.
; Endokrinologický ústav Praha
Published in:
Prakt. Lék. 2007; 87(3): 178-181
Category:
Case Report
Overview
This article describes two cases of female patients who fell ill with thyroid cancer and malignant lymphoma. In the first case, the skin form of non-Hodgkin lymphoma in the left breast was diagnosed. The tumour was excised and the site was treated with radiotherapy at a total dose of 40 Gy. Seven years later the thyroid carcinoma appeared of probable radiogenic origin. A total thyroidectomy and 131I therapy were performed. Both malignancies are currently in long-term remission.
In the second case, a thyroid cancer was first documented. Long-term remission was achieved through the standard procedure of thyroid cancer treatment (surgery and 131I therapy). Eight years later enlarged neck lymph nodes appeared as the first sign of Hodgkin disease. Despite two years of haematological therapy the patient died.
Key words:
thyroid cancer, Hodgkin disease, non-Hodgkin lymphoma.
Labels
General practitioner for children and adolescents General practitioner for adultsArticle was published in
General Practitioner
2007 Issue 3
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