Treatment of pain in the locomotor apparatus with the non-steroid anti-rheumatic of choice, nimesulid
Léčba bolestí v oblasti pohybového aparátu preferenčním nesteroidním antirevmatikem nimesulidem
Výzkum nových látek s analgetickým a protizánětlivým účinkem pokračuje. Hledají se léčiva s minimem nežádoucích účinků, protože se jedná o léčbu obvykle podávanou dlouhodobě. Nimesulid se stává jedním z takových léčiv, protože se řadí mezi tzv. preferenční nesteroidní antirevmatika (má některé vlastnosti neselektivních nesteroidních antirevmatik a zároveň preferenční inhibiční aktivitu směrem k cyklooxygenáze- 2) s minimem nežádoucích účinků v oblasti trávicího ústrojí. Hepatotoxicita nimesulidu s neliší od doposud používaných nesteroidních antirevmatik.
Klíčová slova:
revmatické choroby – analgetická léčba – nesteroidní antirevmatika.
Authors:
K. Trnavský
Authors‘ workplace:
IPVZ a Arthrocentrum, Praha
Published in:
Prakt. Lék. 2005; 85(3): 157-159
Category:
Therapy
Overview
Research in new substances with analgetic and anti-inflammatory effects continues. Sought for are therapeutics with a minimum of side-effects because in question is usually long-term treatment. Nimesulid is one of such drugs, being classified among the so-called preferential non-steroid anti-rheumatics (it has certain properties of non-selective non-steroid antirheumatics and simultaneously a preferential inhibitory activity towards cyclo-oxygenase-2) with a minimum of undesirable effects as to the digestive tract. The hepatotoxicity of nimesulid is no different from hitherto applied non-steroid antirheumatics.
Key words:
rheumatic disease – analgetic therapy – non-steroid antirheumatics.
Labels
General practitioner for children and adolescents General practitioner for adultsArticle was published in
General Practitioner
2005 Issue 3
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