Host Immune Response to Infection by Representativesof the Genus Encephalitozoon
Imunitná odpoveď cicavcov na infekciuEncephalitozoon cuniculi
Stav imunitného systému jedinca zohráva kľúčovú úlohu pri regulácii oportúnnych infekcií. V bojiproti intracelulárnym parazitom sa uplatňujú viaceré nešpecifické ako aj špecifické imunitnémechanizmy. Dominantnú úlohu v reakcii na infekciu zástupcami rodu Encephalitozoon mábunkousprostredkovaná imunitná odpoveď. Encephalitozoon cuniculi, ako najviac preskúmaný zástupcatohto rodu, je schopný prežívať v organizme hostiteľa aj napriek jeho aktívnej imunitnej odpovedi.Latentná asymptomatická infekcia prebieha len dovtedy, kým sú množenie parazita a imunitnáodpoveď v rovnováhe. Preto je dôležité poznať imunitné mechanizmy, ktoré sa zúčastňujú nazvládnutí tejto infekcie.
Klíčová slova:
Mikrosporídia – Encephalitozoon cuniculi – imunológia.
Authors:
A. Valenčáková; F. Lešník; P. Bálent
Authors‘ workplace:
Univerzita veterinárskeho lekárstva, Košice
Published in:
Epidemiol. Mikrobiol. Imunol. , 2004, č. 3, s. 136-141
Category:
Overview
The immunity systemstatus of an individual plays the key role in regulation of opportune infection.In the fight against the intracellular parasites several non-specific as well as specific immunitymechanisms are applied. The dominant role in response to infection caused by the representativesof genus Encephalitozoon plays the cell-mediated immune response. Encephalitozoon cuniculi, asthe most explored representative of this genus is able to survive in the host organism despite hisactive immunity response. Latent asymptomatic infection goes on only as long as the parasitemultiplication and immune response are balanced.
Key words:
Microsporidia – Encephalitozoon cuniculi – immunology.
Labels
Hygiene and epidemiology Medical virology Clinical microbiologyArticle was published in
Epidemiology, Microbiology, Immunology
2004 Issue 3
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