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Problem of Specifi- city of Serological Diagnostic Tests in Legionellosis


Problém špecificity sérologických diagnostických testov pri legionelóze

Imúnne králičie séra a séra pacientov s legionelózou, leptospirózou, Q-horúčkou a protilátkami proti Borrelia burgdorferi sa vyšetrovali v krížových reakciách. V bežne používaných sérologických testoch, nepriamej imunofluorescencii a mikroaglutinačnom teste, sa nezistili protilátky, ktoré by mohli robiť ťažkosti pri interpretácii výsledkov v diagnostike legionelóz. U jedného pacienta sa dokázala zmiešaná infekcia – Q-horúčka a legionelóza.

Klíčová slova:
sérologická diagnostika legionelóz – špecificita testov.


Authors: S. Bazovská 1;  M. Špaleková 1;  E. Kmety 1;  J. Jareková 1;  E. Kováčová 2
Authors‘ workplace: Ústav epidemiológie, Lekárska fakulta Univerzity Komenského, Bratislava 2 Virologický ústav, Slovenská akadémia vied, Bratislava 1
Published in: Epidemiol. Mikrobiol. Imunol. , 1998, č. 4, s. 141-144
Category:

Overview

Immune rabbit sera and sera of patients with legionellosis, leptospirosis, Q fever and antibodies against Borrelia burgdorferi were examined in cross reactions. In currently used serological tests, indirect immunofluorescence and the microagglutination test no antibodies were detected which could cause difficulties in the interpretation of results in the diagnosis of legionellosis. In one patient a mixed infection with Q fever and legionellosis was found.

Key words:
serological diagnosis of legionellosis – specificity of tests.

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Labels
Hygiene and epidemiology Medical virology Clinical microbiology

Article was published in

Epidemiology, Microbiology, Immunology


1998 Issue 4
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