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Utilization of neonatal screening in monitoring of iodine status


Authors: Světnička Martin 1,2;  Hedelová Monika 3;  Vinohradská Hana 4;  El-Lababidi Eva 1,2
Authors‘ workplace: Klinika dětí a dorostu, 3. lékařská fakulta, Univerzita Karlova, a Fakultní nemocnice, Královské Vinohrady, Praha 1;  Centrum pro výzkum výživy, metabolismu a diabetu, 3. lékařská fakulta, Univerzita Karlova, Praha 2;  Laboratoř novorozeneckého, screeningu, Klinika dětí, a dorostu, 3. lékařská, fakulta, Univerzita Karlova, a Fakultní nemocnice, Královské Vinohrady, Praha 3;  L aboratoř novorozeneckého, screeningu, Oddělení, dětské hematologie, a biochemie, Lékařská fakulta, Masarykova univerzita, a Fakultní nemocnice Brno 4
Published in: Čes-slov Pediat 2024; 79 (3): 142-144.
Category: Prevention in pediatrics
doi: https://doi.org/10.55095/CSPediatrie2024/021

Overview

The iodine supply of pregnant and lactating women is crucial for the health of the fetus and newborn, especially for the proper function of the thyroid gland. Inadequate iodine saturation can lead to serious consequences, including permanent health damage to the child. In the Czech Republic, we use neonatal TSH obtained within the Nationwide Newborn Screening Program for Congenital Hypothyroidism to monitor the iodine supply of newborns. The monitoring results were favorable until recently (until 2018 in Bohemia and until 2022 in Moravia); however, in recent years, there has been an increase in the percentage of newborns with elevated TSH, indicating a deepening iodine deficiency in this vulnerable population. One of the reasons may be inadequate iodine supplementation of pregnant women beyond the normal dietary intake (i.e., 150–200 µg of iodine per day) and a decrease in the consumption of dairy, eggs and iodized salt. The Czech Republic must now focus again on this at-risk population regarding the deepening iodine deficiency. It is important to focus primarily on educational activities and ensure adequate iodine supplementation during pregnancy.

Keywords:

Iodine – neonatal screening – iodine deficiency


Sources

Korespondenční adresa:

MUDr. Martin Světnička
Klinika dětí a dorostu, FNKV a 3. LF UK v Praze
Šrobárova 1150/50
100 34 Praha 10
martin.svetnicka@fnkv.cz

1.           Zimmermann MB, Boelaert K. Iodine deficiency and thyroid disorders. Lancet Diabetes Endocrinol 2015; 3(4): 286–95.

2.           WHO, UN Children’s Fund, International Council for the Control of Iodine Deficiency Disorders. Assessement of iodine deficiency disorders and monitoring their elimination. A guide for programme managers, 3rd edn. Geneva: World Health Organization, 2007: 40–41.

3.           Hníková O, Vinohradská H, Dejmek P, et al. Dlouhodobé zkušenosti z monitorování jodového zásobení novorozenecké populace v České republice. Ces-slov Pediat 2014; 69(4): 228–233.

4.           Jiskra J, Límanová Z. Doporučení pro prevenci, časný záchyt a léčbu tyreopatií v těhotenství 2018. Česká endokrinologická společnost ČLS JEP, 2018. Dostupné na: http://www.endokrinologie.cz/cs/doporuceni-pro-prevenci-casny-zachyt-a-lecbu-tyreopatii-v-tehotenstvi-novelizace-9-2023

5.           Mozaffarian D, Rimm EB. Fish intake, contaminants, and human health: evaluating the risks and the benefits. JAMA 2006; 296(15):1885–1899.

Labels
Neonatology Paediatrics General practitioner for children and adolescents

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Czech-Slovak Pediatrics

Issue 3

2024 Issue 3
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