Diabetes
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How Does Empagliflozin Stand in Terms of Diabetic Retinopathy Risk? We Have Answers Not Only from Controlled Studies but Also from Real Practice
Modern antidiabetics – gliflozins and glucagon-like peptide-1 receptor agonists (GLP-1RA) – significantly help improve the management of type 2 diabetes (DM2). In addition to reliable glycemic control, they offer other benefits. For example, gliflozins are known for their cardio- and renoprotective properties. GLP-1RA also reduce cardiovascular (CV) risk, though clinical evaluation (SUSTAIN-6) suggests a possible higher risk of retinopathy. This is also being investigated with gliflozins. How empagliflozin fares in this respect has been…
The Significance of Administering Gliflozins in Real Practice in Diabetics Without CV and Renal Disease
Current care standards recommend the use of sodium-glucose cotransporter 2 inhibitors (SGLT2i,…
Benefit of Empagliflozin in Patients with Chronic Kidney Disease – Results of the EMPA-KIDNEY Study
The sodium-glucose cotransporter 2 inhibitor (SGLT2i) empagliflozin is currently used to treat type…
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How to Set Individual Treatment Goals for Type 2 Diabetes?
Treatment goals for type 2 diabetes should always be set individually. In practice, this…
DPP-4 Inhibitors May Prevent SARS-CoV-2 Entry into Cells
Since the new type of coronavirus SARS-CoV-2 utilizes the DPP-4 receptor to enter human cells,…
Algorithm for Choosing Antidiabetics in Patients with Type 2 Diabetes
As of June 1, 2020, general practitioners can prescribe antidiabetics from the group of…
How to Improve Diabetic Adherence?
The dream of every doctor is a conscientious patient who follows the prescribed treatment and reports...
Impact of Empagliflozin on the Risk of Cardiovascular Death and Need for Hospitalization Due to Heart Failure
In the EMPA-REG OUTCOME study, empagliflozin reduced the risk of cardiovascular death and the number...
Mechanisms Connecting Diabetes Mellitus and Obesity
Obesity has a close relationship with insulin resistance and diabetes mellitus (DM); weight gain...
Combination of SGLT2 inhibitors with metformin in terms of mechanism of action
In the treatment of type 2 diabetes (T2D), metformin is recommended as the first-line drug alongside...
Favorable effect of linagliptin on renal endothelial functions in patients with type 2 diabetes mellitus
Diabetic nephropathy is the cause of up to 50% of cases of end-stage chronic kidney disease. The...
Regular Walking as an Intervention to Support the Quality of Life of Diabetics
Diabetes mellitus (DM), as a chronic and in many cases disabling disease, limits patients in various...
Documented Cardiovascular Benefit of Empagliflozin in New American Diabetes Treatment Guidelines
Two leading overseas medical professional societies, the American Diabetes Association (ADA) and...
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