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Colorectal Cancer

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Benefit of Adding Panitumumab to Maintenance Therapy in mCRC with Non-mutated RAS Oncogene

14. 10. 2023 Source: Colorectal Cancer

PANAMA was the first randomized study evaluating the addition of an anti-EGFR antibody to maintenance therapy with fluorouracil and folic acid (FU/FA) in patients with previously untreated metastatic colorectal cancer (mCRC) with a non-mutated (wt − wild-type) RAS oncogene. The results suggest that upon achieving disease control after initial treatment with FOLFOX + panitumumab, the combination of panitumumab with FU/FA might be the most suitable for maintenance therapy.

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Combination of Targeted Therapy with Chemo in 1st Line in Patients with Left-Sided wtRAS mCRC

The preferred targeted therapy added to the combination with standard chemotherapy (CHT) for…
9. 6. 2023 Source: Colorectal Cancer
kolkar

Early Tumor Regression as a Marker of Overall Survival in First-Line Treatment of mCRC

In the treatment of metastatic colorectal cancer (mCRC), prognostic factors besides overall…
21. 4. 2023 Source: Colorectal Cancer

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Maintenance Therapy After Oxaliplatin Discontinuation Based on Panitumumab

Panitumumab is an approved therapy for metastatic colorectal cancer without RAS oncogene…
20. 2. 2020 Source: Colorectal Cancer

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