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Orally Administered Berotralstat in the Prevention of Hereditary Angioedema Attacks
Berotralstat is an oral medication administered once daily, developed to prevent hereditary angioedema (HAE) attacks. It is a kallikrein protease inhibitor, which plays a key role in the pathogenesis of this disease. A phase III clinical trial, with results recently published in the Journal of Allergy and Clinical Immunology, evaluated the efficacy and safety of two dosing regimens of berotralstat compared to placebo in patients with HAE.
Current (and Future) Possibilities for Diagnosing Alpha-1-Antitrypsin Deficiency
Alpha-1-antitrypsin deficiency (AAT) is associated, among other things, with the development of…
How and What the National AATD Register Benefits Experts and Patients
Given that alpha-1-antitrypsin deficiency (AATD) is still not receiving enough attention, it is…
How and How the Czech National Hemophilia Program Benefits Professionals and Patients
The Czech National Hemophilia Program (ČNHP) has been an interdisciplinary initiative for many…
Analgesic Effects of Using Ringer's Solution in Wound Healing Management
Pain resulting from skin defects of various etiologies causes significant discomfort for the…
Wound Treatment Without Pain? A Rinse Solution Can Help
Patients dealing with a healing wound may fear painful dressing changes. The wound bed is exposed…
How to recognize amyloidosis as a cause of heart failure?
Although the fate of patients with heart failure has improved in recent decades, it remains a…
Inosine pranobex in the treatment of influenza and other respiratory infections of viral etiology
The antiviral inosine pranobex is a clinically proven immunomodulator for the treatment of patients…
Maintaining Therapeutic Doses of Levothyroxine Throughout Shelf Life
Levothyroxine is the drug of choice for patients with hypothyroidism. However, it is also one of…
Is there a link between Parvovirus B19 infection and autoimmune thyroid diseases?
Autoimmune thyroid diseases are among the most common autoimmune disorders, with a worldwide…