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Collagen Turnover as a Biomarker of Hemophilia Treatment Efficacy
Over the past decades, hemophilia treatment has made significant progress—from factor therapy to prophylactic regimens and non-factor products, and even to gene therapy. Its development has greatly improved the quality of life for hemophiliacs and reduced the incidence of bleeding episodes. However, they cannot be completely eliminated, which is why further options for monitoring bleeding and joint status are still being explored. In addition to classical methods, biomarkers are attracting attention, but their practical use is still the…

Alarming Data on Prevalence and Insufficient Treatment of Hypertension in Working Age − Another Underestimated 'Civilization Epidemic'?
The National Cardiology Information System (NKIS), developed by the Czech Society of Cardiology in…

With Prof. Pavel Žák about Current Trends and Future Perspectives in Bone Marrow Transplantation and the Role of Carmustine in this Context
Hematopoietic stem cell transplantation has an indispensable place in the treatment of…

Current Trends in Proton RT of Head and Neck Tumors: Aiming to Preserve T Lymphocytes, Without Them, Treatment is Ineffective
Tumors of the head and neck are often diagnosed at an advanced stage. With the availability of…

What Effect Can Be Expected from Limosilactobacillus reuteri in Mucositis and Peri-Implantitis?
A Spanish clinical study monitored the effect of administering probiotics as an adjunct therapy to…

X-ray in Dentistry: Who Can Indicate and Who Can Perform?
X-ray is an integral and important part of dental diagnostics. However, since it is also a source…

Long-term survival of a 50-year-old man with metastatic pancreatic cancer on a combination of nal-IRI + 5-FU/LV in 2nd line treatment − case study
A recently published case study from the Czech Republic describes a patient with progression of…

Human Papillomavirus in Adults – HPV Does Not Choose Gender
A significant part of the population is exposed to human papillomaviruses (HPV) throughout their lives....

Safety of Metamizole in Adult Patients – Meta-analysis of 79 Studies
Metamizole is a non-opioid analgesic with antipyretic and spasmolytic effects that has been used…