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Lurasidone in the Treatment of Adolescent Schizophrenia: How Does It Compare with Other Atypical Antipsychotics?

27. 9. 2022 Source: Modern Treatment of Schizophrenia

A meta-analysis of 13 studies comparing lurasidone with other atypical antipsychotics in monotherapy for adolescent patients with schizophrenia evaluated the effectiveness of the treatment, the rate of weight gain, and the frequency of medication discontinuation for each modality.

Transition from Risperidone to Lurasidone and Adjustment of Metabolic Profile in Patients with Stable Schizophrenia

Patients with schizophrenia have a higher risk of cardiometabolic diseases compared to the general population, which is further increased by certain antipsychotics. A recently published post hoc…

27. 9. 2022 Source: Modern Treatment of Schizophrenia

Bacterial Community Pneumonia and Its Treatment in Children

Bacterial infections remain a significant cause of child morbidity and mortality. The authors of a recent review published in the journal Pediatric Drugs focused on the treatment of complicated…

26. 9. 2022 Source: Anti-Infectives

Frequency of Participation in Sports Activities and the Risk of Injury in Children with Hemophilia

In children with hemophilia, numerous positive effects of physical activity on their health have been described. However, due to concerns about injuries and joint bleeding, young hemophiliacs may…

22. 9. 2022 Source: Hemophilia with Movement

Modification of Criteria for Diagnosing Irritable Bowel Syndrome in Clinical Practice

The Rome criteria for diagnosing disorders of gut-brain interaction (DGBI) have recently been modified due to discrepancies with their use in clinical practice. The Rome Foundation board has created…

20. 9. 2022 Source: Irritable Bowel Syndrome

Prediabetes as a Risk Factor for Overall Mortality and Development of CVD

Prediabetes represents a glucose metabolism disorder with a high risk of developing diabetes. According to the expert panel of the American Diabetes Association (ADA), this risk is up to 70%. A…

16. 9. 2022 Source: Modern Treatment of Diabetes

XR vs. IR Form of Metformin −⁠ It’s Not Just About Gastrointestinal Tolerability

It is well known that the XR form of metformin shows better gastrointestinal tolerability. However, research suggests that the two forms of metformin −⁠ XR and IR −⁠ differ in other aspects as well. In…

16. 9. 2022 Source: Modern Treatment of Diabetes

What affects the elimination of bisoprolol in diabetics and patients with acute coronary syndrome?

Beta-blockers are widely used to reduce cardiovascular (CV) risk in a number of diseases. However, information about the pharmacokinetics of these drugs is still far from complete. Two studies…

16. 9. 2022 Source: Cardiovascular Continuum

What is the Impact of Bisoprolol on Plasma Concentrations of Dabigatran

Many patients on anticoagulant therapy with dabigatran also use the beta-blocker bisoprolol. The Slovak prospective observational study was based on the assumption that bisoprolol, as a significant…

16. 9. 2022 Source: Cardiovascular Continuum

Interchangeability of Diosmin and Micronized Purified Flavonoid Fraction

Among the medicinal products reimbursed for chronic venous disease, those containing micronized diosmin (Diozen 180 tbl.) have been newly included. Which substances are available for this indication,…

16. 9. 2022 Source: Venous Insufficiency

Ceftaroline as a Treatment Option for MRSA-Induced Sepsis?

A recently published study by a team of authors from several American institutions focused on comparing the efficacy and safety of the 5th generation cephalosporin ceftaroline with the standard of…

16. 9. 2022 Source: Anti-Infectives

Association of Low TSH Levels in Hypothyroidism Therapy with Mortality Risk

Community surveys indicate that up to 53% of patients treated for hypothyroidism have serum thyroid-stimulating hormone (TSH) levels outside the normal range at some point. The negative effect of TSH…

14. 9. 2022 Source: Thyroid Disorders

Correlation of Levothyroxine Dose with Autoimmune Antibody Titer in Primary Hypothyroidism

The relationship between the level of antithyroid antibodies and the required dose of levothyroxine in substitution for autoimmune hypothyroidism is a poorly explored question. Therefore, a…

14. 9. 2022 Source: Thyroid Disorders

Bimekizumab vs. Adalimumab in the Treatment of Moderate to Severe Plaque Psoriasis

Bimekizumab is a humanized IgG1 monoclonal antibody that selectively inhibits interleukins 17A and 17F for the treatment of moderate to severe plaque psoriasis in adults for whom systemic therapy is…

12. 9. 2022 Source: Psoriasis

How to Most Effectively Delay Skeletal Events in Patients with Bone Metastases from Solid Tumors?

In a randomized Phase III study, the effectiveness of denosumab and zoledronic acid in preventing skeletal events in patients with multiple myeloma or solid tumors (excluding breast and prostate…

12. 9. 2022 Source: Prevention of Bone Events

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