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Osimertinib in the Treatment of Patients with NSCLC with Secondary EGFR T790M Mutation – Case Study
Non-small cell lung cancer (NSCLC) is a genetically heterogeneous disease. Individualization of therapy based on the presence of specific tumor cell mutations is therefore crucial for choosing the optimal therapy for these patients. One of the targeted treatment options for patients with NSCLC with an activating mutation in the epidermal growth factor receptor (EGFR) gene is osimertinib, a third-generation EGFR tyrosine kinase inhibitor (EGFR TKI). We present a case study of a patient with NSCLC treated with osimertinib after disease…
Chronic Thromboembolic Pulmonary Hypertension – Overview of Pathophysiology, Diagnosis, and Treatment
Chronic thromboembolic pulmonary hypertension (CTEPH) is defined by the 2015 ESC/ERS guidelines as…
Effect of Cataract Surgery on Melatonin Secretion in Adults Aged 60 and Over
A study by ophthalmologists and epidemiologists from Nara University in Japan, recently published…
Morning Myopic Shift and Glare in Patients with Advanced Fuchs Endothelial Corneal Dystrophy
A newly published study by a German team analyzes the morning and afternoon differences in various…
Venetoclax in the Treatment of CLL: Open Doors for the Longest Possible Maintenance of Remission Without Active Therapy
William G. Wierda from MD Anderson Cancer Center in Houston, USA, and Francesco P. Tambaro from…
Temporary Interruption of Treatment or Dose Modification of Ibrutinib in CLL Patients
A team from the Mayo Clinic in Rochester, USA, published a study this March in the journal Cancer…
Valproate and Lithium in Maintenance Therapy of Bipolar Affective Disorder
Among the so-called mood stabilizers, drugs commonly used in the therapy of bipolar affective…
Anticonvulsants Are Associated with the Least Impact on Sexual Function in Bipolar Disorder Treatment
It is known that in patients with bipolar disorder, in addition to the illness itself, sexual…
Study PLATON: romiplostim in patients with ITP in real clinical practice
Recently, the results of the PLATON study with romiplostim, which was conducted in Central and…
Pediatric Immune Thrombocytopenia Does Not Overlap with Adult ITP
Immune thrombocytopenia (ITP) is a highly heterogeneous disease characterized by various bleeding…