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Algorithm for Choosing Antidiabetics in Patients with Type 2 Diabetes
As of June 1, 2020, general practitioners can prescribe antidiabetics from the group of so-called gliptins, inhibitors of the enzyme dipeptidyl peptidase 4 (DPP-4i), in addition to metformin. The cornerstone of type 2 diabetes mellitus treatment remains a comprehensive lifestyle modification (dietary measures, increased physical activity, weight reduction) and metformin as the first-line drug. In selected comorbidities or if these measures do not lead to the desired glycated hemoglobin (HbA1c) level after 3-6 months, the following…
Major Orthopedic Procedures in Patients with Inhibitor Treated with Emicizumab
Italian authors presented the results of a study of a small series of hemophilia patients with…
Comorbidities of Migraine and Their Impact on Pain Frequency and Intensity
The MAST study, published in March of this year in the prestigious The Journal of Headache and…
What is the significance of hormones in the pathophysiology of migraine?
Migraine is a complex neurovascular disease characterized by the dysfunction of the nociceptive…
When to Initiate Dabigatran Therapy in Patients with Atrial Fibrillation After First Ischemic Stroke?
After a cardioembolic ischemic stroke (iCMP), approximately 5% of patients experience a recurrence…
Trazodone as an Effective Medicine in the Therapy of Depression and Insomnia
Trazodone (Trittico®) is a medicine indicated for the treatment of depression, which has also been…
Inflammation, Polyunsaturated Fatty Acids and Their Significance in the Development and Treatment of Depression
Depression is currently a highly discussed disease with a prevalence that is likely to rise.…
What Next for Patients with CLL After Stopping Venetoclax?
Standard care for untreated patients with chronic lymphocytic leukemia (CLL) is therapy based on…
Effect of Initiation of Warfarin Therapy on the Risk of Ischemic Stroke
Anticoagulant therapy is essential in patients with atrial fibrillation for the prevention of…
Current Indication Criteria for Testing Mutations in BRCA1 and BRCA2 Genes in Breast and Ovarian Cancer
Testing the mutation status of the BRCA1/2 genes can be beneficial for prevention, and in the case…