News
Simple antiemetic prophylaxis for breast cancer patients treated with AC chemotherapy
The combination of an anthracycline cytostatic agent with cyclophosphamide (AC) is among the highly effective chemotherapy regimens for breast cancer. Individually, these cytostatic agents carry a moderate risk of emetogenicity; however, when combined, they are considered to be at high risk of emesis. The recommended prophylaxis involves administering a 5-HT3 serotonin receptor antagonist in combination with an NK1 neurokinin receptor antagonist and the corticosteroid dexamethasone.
Observational Study of Pegylated rVIII Administration in Real Clinical Practice
A recently published article by American hematologists provided valuable information about the…
Cost-effectiveness in Bleeding Control for Acquired Hemophilia A
A pharmacoeconomic analysis showed favorable cost-effectiveness of activated prothrombin complex…
Comparison of Efficacy of Bisoprolol and Metoprolol ZOK in Patients with Mild to Moderate Hypertension – Results of the CREATIVE Study
Suppression of increased activity in the sympathoadrenal system is currently one of the main goals…
Impact of Adequate Protein Intake on Morbidity and Mortality in Critically Ill Patients
The following text provides a summary of findings from clinical studies in the field of nutritional…
How to Achieve Left Ventricular Reverse Remodeling and Improve Outcomes in Heart Failure? Summary from HFA ESC Webinar
The current treatment algorithm for chronic heart failure with reduced ejection fraction (HFrEF) is…
The Importance of Adequate Protein Intake in Critical Patients – Analysis of Data from an International Study
Adequate protein intake is a necessary part of care for critically ill patients and mitigates…
Direct Comparison of the Efficacy and Safety of Anti-EGFR Antibodies in the Combined Therapy of Chemotherapy-Refractory Metastatic Colorectal Cancer
The combination of anti-EGFR therapy with irinotecan has brought benefits to patients with…
Glucagon for Intranasal Application Newly Available Also in the Czech Republic
Intramuscular administration of glucagon was until recently the only option for acute treatment of…
Use of Tiapride in the Treatment of Behavioral Disorders in Geriatric Patients
Hand in hand with the increasing number of people reaching an older age, there is also a rise in…