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Does idarucizumab reverse the anticoagulant effect of dabigatran regardless of renal function?

29. 3. 2021 Source: Anticoagulant Treatment

The drugs idarucizumab and dabigatran are excreted by the kidneys. The RE-VERSE AD study investigated whether the renal function of patients affects the extent of the reversing effect of idarucizumab on the effect of dabigatran.

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Profile of the effect of aclidinium bromide compared to glycopyrronium bromide

A study by Spanish authors examined the profiles of 2 long-acting muscarinic receptor antagonists (LAMA), aclidinium bromide and glycopyrronium bromide, under in vitro and in vivo conditions.
29. 3. 2021 Source: Treatment of Asthma and COPD
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Genuair®/Pressair® Inhaler in the Treatment of COPD –⁠ Minimum Errors During Inhalation and High Patient Satisfaction

The article by German authors summarizes the results achieved with the Genuair® inhaler (marketed in the USA under the name Pressair®), highlighting its ease of use, simple patient training, low…
29. 3. 2021 Source: Treatment of Asthma and COPD
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The Importance of Vitamin D for the Proper Function of the Immune System

The relationship between vitamin D and the immune system has been known for nearly 30 years, but only in recent years have we gained new insights that explain and further refine the physiological…
29. 3. 2021 Source: GI, colic and microbiome
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Summary of Recommendations for the Treatment of Immune Thrombocytopenia in Pregnancy

Immune thrombocytopenia (ITP) is an autoimmune disorder characterized by a temporary or permanent reduction in the number of platelets, leading to an increased risk of bleeding. It also occurs in 1-5…
28. 3. 2021 Source: Immune Thrombocytopenia
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Teriflunomide and Pregnancy Planning

The authors of the article published last year in Multiple Sclerosis Journal present data regarding experiences with the use of teriflunomide during pregnancy.
25. 3. 2021 Source: Multiple Sclerosis
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Interactive Case Study of a Patient with Severe Hemophilia A -⁠ Experience from Slovenia

Assoc. Prof. Dr. Irena Preložnik Zupan (University Medical Centre Ljubljana) describes an interactive case study of a patient with severe hemophilia A and progressive cataracts in both eyes.
24. 3. 2021 Source: Quality Life Even with Hemophilia
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New Treatment Options for Hemophilia Come with Discussions on Important Issues

The organizing committee of this year's virtual congress of the European Association for Haemophilia and Allied Disorders (EAHAD 2021) promised in the opening speech a "showcase of the latest…
24. 3. 2021 Source: Quality Life Even with Hemophilia
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Summary Analysis of HAVEN 1–4 and Patient Case Studies from ÚHKT

MUDr. Věra Geierová from the Institute of Hematology and Blood Transfusion in Prague prepared a summary of what was discussed about emicizumab during the ASH 2020 congress for this year's Prague…
24. 3. 2021 Source: Quality Life Even with Hemophilia
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Detection of von Willebrand Disease

Von Willebrand disease (vWD) is an autosomal hereditary bleeding disorder. Its detection and diagnosis require several steps, including the initial suspicion of the presence of this disease.
23. 3. 2021 Source: Von Willebrand Disease
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