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Prenatal Phenotype of Children with Noonan Syndrome
Until recently, the various phenotypes of RASopathies were clinically diagnosed only after birth. However, we are now striving for the earliest possible diagnosis, sometimes even prenatally. Ultrasound examination of the fetus during screening tests, focusing on certain characteristic morphological changes, plays a crucial role in this. In the case of pathological findings on imaging methods, molecular genetic testing and monitoring of pregnancy in specialized centers are indicated.

Biological treatment of psoriatic arthritis in the 1st line – results of the SPIRIT-H2H study after 1 year of follow-up
The SPIRIT-H2H study compared the efficacy of ixekizumab and adalimumab, either as monotherapy or…

Perioperative Thromboprophylaxis in Elderly Patients
Thromboembolic disease (TED) is among the most common causes of death in hospitalized patients and…

Extended Thromboprophylaxis with Enoxaparin After Bariatric Surgery
A recent retrospective study involving 312 patients after bariatric surgery indicated that extended…

Diagnosis of von Willebrand Disease Step by Step
Von Willebrand disease (vWD) is the most common congenital bleeding disorder, with an estimated…

Diabetic Nephropathy and COVID-19: Fatal Connection?
People with diabetes and diabetic kidney disease exhibit higher mortality and risk of severe…

Role and Possibilities of Telemedicine in the Management of Hemophilia Care
A team of Irish experts recently evaluated the current possibilities of telemedicine in the care of…

Manual Fascial Therapy in Patients with Hemophilic Arthropathy
Fascial therapy is a rehabilitative technique that mobilizes the fascial complex using manual…

Metamizole vs. Tramadol in Postoperative Analgesia
Metamizole and tramadol are well-known analgesics that have been used in practice for a long time.…

Spasmolytic Effect of Metamizole
A study aimed at clarifying the mechanism of action of metamizole suggested that the clinically…