Why do some patients with endometriosis have only small lesions yet suffer from unbearable pain, while others with extensive lesions feel almost none? An international team of scientists, in collaboration with the Sbarro Health Research Organization (SHRO), may have found the answer.
Dnešní „jednohubky“ takřka monotematicky věnujeme především kardiovaskulárnímu zdraví a prevenci.
It is not only the home of a legendary scientist said to have made a pact with the devil, but also the site of the Hemodialysis Center of the General University Hospital (VFN). At Prague’s Faust House, representatives of the Department of Nephrology of the First Faculty of Medicine, Charles University, and VFN in Prague commemorated a unique milestone — the performance of the first hemodialysis not only in former Czechoslovakia, but in the entire socialist bloc.
A study published in Nature Communications presents a system that enables deep brain stimulation without the need for surgery. According to the authors, the device is the first capable of modulating deep brain regions approximately 1,000 times smaller than those accessible with conventional ultrasound devices, and 30 times smaller than those targeted by previous systems designed for deeper brain structures.
Bulovka University Hospital (FNB) joined the ranks of Czech hospitals using robotic assistance in surgery on Three Kings’ Day (January 6). The ceremonial ribbon was cut — in the presence of Hospital Director Mgr. Jan Kvaček and MUDr. Martin Šnajdauf, Ph.D. — by the Da Vinci Xi robot itself. At the request of the staff, the new robotic operating room was subsequently blessed by the hospital chaplain.
Why is knowledge from mountain medicine valuable even in countries where high mountain ranges are not readily available? What attracts medical students to this field, and what are the latest scientific insights? All this was presented to MeDitorial by MUDr. Lenka Horáková, Ph.D., from the Department of Anesthesiology, Intensive and Emergency Medicine of the Third Faculty of Medicine, Charles University, and Bulovka University Hospital in Prague.
The first “bites” of the year highlight, right at the start, the benefits of a month of alcohol abstinence. Alongside this, they move from the latest findings on outcomes of proton therapy for oropharyngeal cancer through predictors of dementia all the way to prodromal dreams.
Disruption of transport mechanisms across the blood–brain barrier is considered one of the key factors contributing to β-amyloid accumulation in the brain. A new experimental study shows that modifying the avidity of ligands for the LRP1 receptor can influence its intracellular trafficking and restore transcytosis across the endothelium, opening up new therapeutic possibilities for Alzheimer’s disease.
An international study examined the views of clinical physicians from six countries regarding the acceptability of euthanasia for people living with dementia. The survey revealed substantial disagreement among experts on this topic.
The overuse of antibiotics has helped bacteria become resistant to them. In the fight against antibiotic resistance, the involvement of artificial intelligence in the development of new drugs could prove beneficial. Using AI, experts from MIT examined more than 36 million possible compounds and evaluated their antimicrobial properties. The researchers also analyzed potential new compounds that had not yet been synthesized. The best candidate molecules discovered are structurally distinct from all existing antibiotics and appear to disrupt…
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