Systematický přehled a metaanalýza studií z let 2011–2024, provedené týmem z Dětského centra Johnse Hopkinse, ukazují, že některé videohry vyvinuté jako digitální intervence mohou být užitečným doplňkem péče u dětí a adolescentů s úzkostnými poruchami, depresí nebo poruchou pozornosti s hyperaktivitou (ADHD).

Dogs have an extraordinary sense of smell, which humans use across a wide range of fields —⁠ including medicine. A recently published study investigated whether dogs could assist in diagnosing Parkinson’s disease (PD) using their olfactory abilities. How did these four-legged investigators perform?

Gerstmann-Sträussler-Scheinker syndrome (GSS) is a prion disease of the brain. It is an extremely rare but invariably fatal disorder in which a normal protein becomes a destructive pathogen. Although GSS occurs only in a few cases per 100 million people, studying it may help unravel mechanisms underlying neurodegenerative diseases.

The accelerated approval of elamipretide by the U.S. FDA marks a historic milestone in the treatment of mitochondrial diseases. It is the first therapy targeting cardiolipin dysfunction and the first approved drug for patients with Barth syndrome —⁠ an ultra-rare, life-threatening disorder that primarily affects boys.

On the occasion of this year’s World Chronic Obstructive Pulmonary Disease (COPD) Day, observed on November 19, Czech pulmonologists drew attention to a new topic: the dangerous overlap of COPD and obstructive sleep apnea (OSA). Although this combination has a markedly negative effect on prognosis, it remains significantly underdiagnosed in the long term.

The same virus, yet tumors behave very differently. HPV-positive oropharyngeal squamous cell carcinoma (OPSCC) is highly radiosensitive, enabling treatment de-escalation and thus lowering toxicity. Cervical squamous cell carcinoma (CSCC), caused by the same virus, requires aggressive multimodal therapy. What drives these differences and how do they influence therapeutic strategy?

In September, the Congress of Clinical Microbiology, Infectious Diseases and Epidemiology (KMINE) took place in Hradec Králové. What insights did it bring regarding current and emerging antibiotic therapy? And how might the discussed conclusions translate into everyday antibiotic prescribing? MUDr. Marek Štefan, MBA, from the Department of Infectious Diseases and Travel Medicine, 2nd Faculty of Medicine, Charles University, and Motol University Hospital in Prague, shared his observations on these topics.